Laparoscopic resection of gastric leiomyosarcoma.

Wedge resection with a normal margin of stomach is generally considered adequate therapy for gastric leiomyosarcoma. We report here four patients with gastric leiomyosarcoma managed laparoscopically. The technique is described.

Gastrointestinal effects of NSAIDs. Difficulties in detection and management.

Nonsteroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid are effective analgesic agents, but their use carries a significant potential for gastrointestinal side effects. Because many persons who have serious adverse effects from NSAIDs are asymptomatic, the decision to use these drugs must be tempered by an understanding of the side-effect profile and knowledge of who constitutes the high-risk population. Patients must be vigilantly monitored for signs and symptoms of reactions to the drugs, which should be discontinued when injury is suspected if at all possible.

Effect of fiber and its fermentation on colonic adaptation after cecal resection in the rat.

Background: The role of fiber in postresection adaptation is poorly understood. We examined the significance of short-chain fatty acids produced by intracolonic fiber fermentation during colonic adaptation.

Methods: Rats underwent one of three surgeries: control laparotomy, cecal resection, or cecal resection with placement of perfusion catheter.