Publications by authors named "I A Kalogiannidis"
Importance: Rhesus alloimmunization refers to the sensitization of an Rh D-negative mother after exposure to D-positive fetal red blood cells, which can lead to significant fetal and neonatal morbidity and mortality.
Objective: The aim of this study was to review and compare the most recently published international guidelines on the prevention of maternal alloimmunization.
Evidence Acquisition: A comparative review of guidelines from the American College of Obstetricians and Gynecologists, the British Committee for Standards in Hematology, the International Federation of Gynecology and Obstetrics, the Royal Australian and New Zealand College of Obstetricians and Gynecologists, and the Society of Obstetricians and Gynecologists of Canada regarding the prevention of maternal Rh D alloimmunization was conducted.
Performance of International Ovarian Tumor Analysis (IOTA) predictive models in preoperative discrimination between benign and malignant adnexal lesions: preliminary outcomes in a Tertiary Care Hospital in Greece.
Arch Gynecol Obstet
December 2024
Objectives: To apply the International Ovarian Tumor Analysis (IOTA) predictive models, the logistic regression model 2 (LR2) and the IOTA Assessment of Different NEoplasias in the adneXa (ADNEX), in patients with ovarian masses and to compare their performance in preoperative discrimination between benign and malignant adnexal lesions.
Methods: This was a retrospective diagnostic accuracy study with prospectively collected data, performed between January 2019 and December 2022, in a single tertiary gynecologic oncology center in Greece. The study included women with an adnexal lesion which underwent surgery within 6 months after of using the LR2 and ADNEX protocol to assess the risk of malignancy.
Article Synopsis
- Endometrial cancer is the most common gynecological cancer, and a study compared recent management guidelines from various major oncology societies.
- Key findings showed both similarities and differences in surgical procedures, particularly relating to endometrial biopsy and lymph node involvement.
- The study suggests that creating consistent international protocols could improve classification, surgical methods, risk assessment, and patient monitoring post-remission.
Preterm birth, affecting about 10% of pregnancies, significantly contributes to perinatal morbidity and mortality. Recent research indicates that metabolomics could enhance pregnancy outcomes and reduce costs by identifying biomarkers related to common pregnancy complications. Our team focused on analyzing amniotic fluid collected during the second trimester to identify potential biomarkers for preterm birth using 1H-NMR metabolomic analysis.
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- PPROM is a major cause of health issues for both mothers and newborns during pregnancy, and this review summarizes the latest guidelines for its diagnosis and management from three major medical organizations.
- All guidelines agree that the best way to diagnose PPROM involves a detailed patient history and sterile examination, combined with certain tests, while treatment generally includes swabs, monitoring, and possibly medication or early labor induction if severe complications arise.
- Although there is a consensus on the need for careful monitoring and management of PPROM cases, the guidelines differ on timing for delivery, use of certain medications, and the approach to follow-up for future pregnancies.