Publications by authors named "I A Jacobsen"
Background: Exposure-related changes in exhaled nitric oxide (FeNO) and sputum eosinophils have not been thoroughly compared in the investigation of occupational asthma.
Objective: This study aimed at comparing the accuracies of the changes in FeNO concentrations and sputum eosinophil counts in identifying asthmatic reactions induced by occupational agents during specific inhalation challenges (SICs).
Methods: This retrospective multicenter study included 321 subjects who completed an assessment of FeNO and sputum eosinophils before and 24 h after SICs with various occupational agents, of whom 156 showed a positive result.
Article Synopsis
- Infection with low-risk HPV types 6 and 11 can cause recurrent respiratory papillomatosis (JoRRP) in children, which leads to benign growths in the larynx.
- A systematic review studied the effects of national HPV vaccination programs on the incidence and prevalence of JoRRP, analyzing data from four studies that included 622 patients from countries like Australia, New Zealand, and the U.S.
- Results showed a significant decline in JoRRP cases after vaccination, with higher vaccination rates linking to lower disease burden, highlighting the importance of widespread HPV vaccination for future health outcomes.
To report a rare case of Rosai-Dorfman-Destombes (RDD) disease in a teenage girl exhibiting mild fever, night chills, vertigo, and progressive bilateral vision and hearing loss. Case report of a 15-year-old girl who underwent extensive ophthalmic multimodal imaging and a comprehensive workup evaluation. Multiple choroid lesion masses in both eyes associated with systemic multifocal lymphadenopathy, involvement of the paranasal sinuses, and unusual intracranial manifestations well-shown by magnetic resonance imaging (MRI) and whole-body PET-scan.
View Article and Find Full Text PDFBackground: Developmental Coordination Disorder is a commonly occurring, but poorly recognised developmental condition characterised by difficulties with motor functions. Danish tests of children's motor functioning, which are currently available, are outdated and only applicable up to the age of seven years old. New tools are needed to enable easy and efficient screening of motor difficulties experienced by children living in Denmark.
View Article and Find Full Text PDFArticle Synopsis
- The fungus and Gram-positive bacterium coexist in human mucosal areas and can become harmful when there's an imbalance in microbial populations, leading to serious infections in vulnerable individuals.
- The study reveals that the presence of the bacterium increases damage to host cells caused by the fungus, and this relationship worsens oropharyngeal candidiasis in mice.
- This increased damage is driven by enterococcal cytolysin and is influenced by physical interactions between the bacteria and host cells, as well as changes in glucose availability due to the fungus's metabolic activity.