Publications by authors named "I A Jaafar"
Article Synopsis
- Limited solubility of miconazole nitrate (MN) is a key factor in its low effectiveness against candidiasis, prompting a study to create a microemulsion (ME) and temperature-triggered in situ gel for enhanced delivery.
- Researchers conducted various tests, including solubility studies and the construction of pseudo-ternary phase diagrams to optimize the formulation, ultimately selecting tea tree oil, lavender oil, tween 80, and propylene glycol for the ME.
- The resulting gel formulation (MG1) showed optimal characteristics like gelation temperature, viscosity, and a significant increase in antifungal activity compared to existing MN products, alongside no irritation in animal tests.
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in older adults and has a poor prognosis and limited response to treatment. The growing impact of palliative care on older people undergoing neurosurgery is becoming increasingly important. Palliative care aims to improve the quality of life for people and their families by addressing their physical, psychosocial, and spiritual needs.
View Article and Find Full Text PDFObjective: The aim of the present study was to illustrate the outcomes of abnormally invasive placenta (AIP) cases managed in three leading centers in Lebanon.
Methods: We conducted a retrospective multicenter cohort study. Patients managed conservatively (cesarean delivery with successful placental separation) or radically (cesarean hysterectomy) were included in the study.
Background Objectives: Dengue and chikungunya infections are one of the major health problems that have plagued the human population globally. All dengue virus (DENV) serotypes circulate within Malaysia with particular serotypes dominating in different years/outbreaks. In the state of Kelantan, an increasing number of DENV and chikungunya virus (CHIKV) new cases have been reported, including several deaths.
View Article and Find Full Text PDFIntroduction: Post-stroke spasticity (PSS) is a disorder of the sensory-motor control, leading to upper motor neuron lesions manifesting either as intermittent or sustained involuntary activation of muscles. Botulinum neurotoxin-A (BoNT-A) is mostly utilized in a variety of therapeutic indications, and it is effective and safe in the management of focal PSS in the rehabilitation scenario. The study aimed to evaluate the effect of BoNT-A administration on H-reflex of upper and lower limbs following PSS.
View Article and Find Full Text PDF