[The dynamic changes in the tissue components of the myocardial layers under compensatory heart hypertrophy in exposure to a peptide hydra morphogen].

Morphometric analysis of the left ventricle myocardial layers under heart hypertrophy was carried out. Values of tissue parameters on the 3rd, 10th and 24th days after 50% coarctation of the abdominal aorta were received. Is shown the heart functioning under conditions of myocardial compensatory hypertrophy development is characterized by expressed zones and different directions of changes of quantitative parameters of tissue components.

[Effect of peptide hydra morphogen on the structure of tissue components of rat myocardial layers in the early period of heart hypertrophy development].

The morphological study showed that the single injection of HMP (Hydra Morphogen Peptide) facilitated the development of the myocardium hypertrophy. This effect is expressed in the subendocardial layer most of all, where the normalization of the relative volume and diameter of the cardiomyocytes and the decrease of the connective tissue oedema are noted. These parameters are normalized in the intramural and subepicardial layers in less degree.

[Morphological characteristics of tissue components of various layers of the rat myocardium in the early period of development of myocardial hypertrophy].

The tissue components of the subendocardial, intramural and subepicardial layers of the myocardium of rats were examined by morphometry on the 10 day after 50% subphrenic coarctation of the abdominal aorta. The decrease of the relative volume of cardiomyocytes in the subendocardial layer and the increase of this index in the other layers of myocardium were discovered. The decrease of the surface of cardiomyocytes was maximal in the intramural layer and in the other examined layers the decrease was less.