[The combined chemotherapy with platinum of patients with inoperable non-small cell lung cancer].

Combination chemotherapy with cyclophosphamide, 5-fluorouracil, adriamycin and platinum was performed in 122 patients with stage III-IV squamous-cell cancer and adenocarcinoma of the lung. Control group included 84 cases of non-small-cell lung cancer treated with the same drugs except platinum. Ten patients with stage III disease received platinum-based combination chemotherapy and split-course radiotherapy in the total dose of 65-70 Gy.

[Functional-morphologic changes in the liver in breast cancer].

The functional state of the liver was studied in 239 patients with mammary gland cancer, 34 of them with intravital morphostructure of the organ. A significant impairment of the absorptive and secretory function of hepatocytes was evident. Also, there was noted an impairment of hepatic microcirculation, the decrease of leukoproductive function and enzymatic activity, changes in the content of the urine and blood cholesterol, in microelements of copper and iron.