Publications by authors named "I A Farhat"

Background: Community-acquired pneumonia (CAP) remains a leading cause of infectious disease mortality globally, necessitating intensive care unit (ICU) admission for ∼10% of hospitalised patients. Accurate prediction of disease severity facilitates timely therapeutic interventions.

Methods: Our study aimed to enhance the predictive capacity of the clinical CRB-65 score by evaluating eight candidate biomarkers: troponin T high-sensitive (TnT-hs), procalcitonin (PCT), N-terminal pro-brain natriuretic peptide, angiopoietin-2, copeptin, endothelin-1, lipocalin-2 and mid-regional pro-adrenomedullin.

View Article and Find Full Text PDF

Objectives: Hybrid closed-loop (HCL) systems improve glycemic control in type 1 diabetes mellitus (T1D), but their effectiveness in young, poorly controlled populations is not established and requires study.

Methods: A pre-post study was performed using electronic health records of patients 3-24 years with baseline HbA≥9 % prescribed HCL within the New York City Health+Hospitals System assessing HbA levels and hospitalizations before and after HCL initiation and factors associated with achieving HbA<9 % after HCL initiation.

Results: Of 47 children and adolescents who met inclusion criteria, 4.

View Article and Find Full Text PDF
Article Synopsis
  • Kidney structural cells actively participate in the rejection process of kidney transplants, alongside infiltrated immune cells, as shown through single-cell RNA sequencing of biopsies.
  • Upregulation of immune-related genes was observed in endothelial and epithelial cells, indicating their involvement in the alloimmune response, with distinct differences based on the kidney compartment.
  • A significant downregulation of energy metabolism in proximal tubular cells during inflammation correlates with reduced kidney function, emphasizing the graft's crucial role in driving and maintaining rejection after transplantation.
View Article and Find Full Text PDF

A technique for solving the one-port closed coaxial transmission line sample holder scattering equation for complex permittivity inversion for lossy materials is presented. A non-linear least-squares procedure is used for the determination of parameters for the specification of the spectral functional form of the complex permittivity. The method allows for accurate retrieval of many low- and high-permittivity dielectric materials in the frequency range of 1 GHz to 3 GHz inserted into the coaxial cell.

View Article and Find Full Text PDF