Publications by authors named "I A Darby"
Objectives: This study aimed to assess membrane use with a bone substitute graft for guided bone regeneration (GBR) in experimental dehiscence defects.
Materials And Methods: Maxillary second incisors (I2) in 9 dogs were extracted. Six weeks later, implants were inserted and experimental dehiscence defects (5 × 3 mm) created on the buccal aspect.
Article Synopsis
- - Diabetic kidney disease (DKD) is a major cause of kidney failure linked to diabetes and obesity, but effective treatments to slow its progression are currently unavailable.
- - Research on single-cell transcriptomic profiles from DKD patients and mouse models reveals a growing population of macrophages expressing TREM2 in mice fed a high-fat diet, which correlates with obesity and diabetes.
- - In mice lacking TREM2, increased kidney damage and cell injury were observed, indicating that boosting TREM2 macrophages could be a promising therapeutic approach for DKD.