Publications by authors named "I A Danilova"
Article Synopsis
- The study details a case of acute humoral rejection (AMR) in a heart transplant patient who had a history of hypertrophic cardiomyopathy and chronic myocarditis.
- After the transplant, the patient faced complications like pneumonia, leading to reduced immunosuppressive therapy.
- Tragically, the patient suffered a fatal hemodynamic collapse linked to autopsy findings of AMR with significant presence of CD16+ cells and SARS-CoV-2 Spike protein, highlighting the need for further research on the virus's impact on AMR.
Under the influence of inflammation, pancreatic β cells can transdifferentiate into cells with a different phenotype. When inflammation decreases, the opposite process is possible. We studied the effect of intramuscular injection of 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt (APH) on the structural and functional characteristics of the pancreatic islets in rats with experimental type 2 diabetes mellitus.
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- - Boron may improve the effectiveness of proton beam therapy in cancer treatment by enhancing cell damage in the targeted Bragg peak region through a specific nuclear reaction, although some studies have questioned this claim.
- - Experiments with prostate cancer and glioblastoma cells using 190 MeV proton beams showed that boron (from sodium mercaptododecaborate) significantly increased cell killing, especially at low concentrations and in the Bragg peak area.
- - The beneficial effects of boron occur through rare proton-boron reactions generating alpha particles, which lead to enhanced cell death, and this response seems to be amplified through interactions between cells, highlighting its potential for clinical use in treating certain tumors.
Microbiomes influence the physiology and behavior of multicellular organisms and contribute to their adaptation to changing environmental conditions. However, yeast and bacterial microbiota have usually been studied separately; therefore, the interaction between bacterial and yeast communities in the gut of () is often overlooked. In this study, we investigate the correlation between bacterial and yeast communities in the gut of .
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- Type 2 diabetes involves high blood sugar and reduced function of insulin-producing β-cells, prompting research into potential treatments.
- This study tested the effects of betulin, a natural compound from birch bark, on diabetic rats, focusing on various health parameters over a 28-day period.
- Results indicated that betulin improved blood sugar levels and reduced liver and kidney damage in diabetic rats while promoting the regeneration of β-cells, suggesting it could be a promising treatment for diabetes.