Publications by authors named "I A Cree"
Article Synopsis
- The WHO Classification of Tumours (WCT) serves as a key guide for cancer diagnosis and research, but it needs updates based on evolving research evidence.
- A study focused on creating evidence maps for lung and thymus tumors based on the WCT-5, analyzing 1434 studies for lung and 677 for thymus tumors.
- Findings revealed that the majority of studies had low levels of evidence, with only a small percentage classified as high quality, highlighting the need for improvement in future WCT editions.
Article Synopsis
- This report analyzes the references cited in the DCIS chapter of the 5th edition of the WHO Classification of Tumours, focusing on their evidence levels and identifying gaps in knowledge.
- A total of 36 publications were evaluated, revealing that most citations were case series, which are considered low-level evidence, and highlighting an uneven distribution of references across different tumor descriptors.
- The findings suggest a need for more robust studies in areas with fewer citations, and the developed evidence map may help guide future research and improve subsequent editions of the WCT.
Evidence-based medicine (EBM) can be an unfamiliar territory for those working in tumor pathology research, and there is a great deal of uncertainty about how to undertake an EBM approach to planning and reporting histopathology-based studies. In this article, reviewed and endorsed by the Word Health Organization International Agency for Research on Cancer's International Collaboration for Cancer Classification and Research, we aim to help pathologists and researchers understand the basics of planning an evidence-based tumor pathology research study, as well as our recommendations on how to report the findings from these. We introduce some basic EBM concepts, a framework for research questions, and thoughts on study design and emphasize the concept of reporting standards.
View Article and Find Full Text PDFThe recently published WHO Reporting System for Pancreaticobiliary Cytopathology (World Health Organization [WHO] System) is an international approach to the standardized reporting of pancreaticobiliary cytopathology, updating the Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology (PSC System). Significant changes were made to the categorization of benign neoplasms, intraductal neoplasms, mucinous cystic neoplasms, and malignant neoplasms considered low grade. Benign neoplasms, such as serous cystadenoma, categorized as Neoplastic: benign in the PSC system, are categorized as Benign/negative for malignancy in the WHO system.
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