[The problems of identification of various strains of vegetative form of Bacillus anthracis using MALDI-ToF MS technique.].

The article considers experience of application of mass-spectrometry with matrix-activated laser desorption/ionization for fast and reliable identification of Bacillus anthracis and heterologous species of microorganisms. The particular interesting characteristics and difficulties occurred during identification are covered.

[The diagnostic significance of particular immune-dominating proteins of isogenic variants of Bacillus Anthracis.].

The polyclonal mono-specific sera to proteins of toxin and antigens of S-layer of Bacillus Anthracis separated in preparative electrophoresis. While fluorescent antibody technique was applied, immunoglobulins of sera to protein of S-layer of Bacillus Anthracis m.m.

[Characteristics of isogenic variants of Bacillus anthracis with various content of virulence plasmids].

Aim: Production and characteristics by main cultural-morphologic and antigenic properties of isogenic variants Bacillus anthracis, that differ by the presence of virulence plasmids.

Materials And Methods: B. anthracis 81/1, 575/122 virulent and B.

[The optimization of algorithm of laboratory diagnostic of Western Nile fever in territory of Russia].

The article deals with results of study of antigenic chiasms between viruses of Western Nile fever and tick-borne encephalitis using binding immunoassay applied to blood serum from patients residing in various regions of Russia. It is established that to get accurate laboratory diagnostic it is reasonable to apply the proposed algorithm of analysis in which alongside with binding immunoassay such differential criterion as positivity rate is to be implemented to speed up and simplify laboratory diagnostic of infections brought on by viruses of Western Nile fever and tick-borne encephalitis.

[Species-specific sera against surface antigens of Bacillus anthracis strains].

The species-related specificity of sera against 94-KD proteins isolated from culture filtrates of B. anthracis strains with different levels of virulence plasmids was studied to determine whether they might be used to identify the pathogen of anthrax. Sera against fractions 1 of culture filtrates of B.