[Structural and functional features of the main arteries of the brain and tumor necrosis factor-alpha in people with chronic non-infectious diseases].

Objective: To investigate the structural and functional characteristics of the carotid and vertebral arteries and their relationship with tumor necrosis factor-alpha (TNF-α) levels in patients with chronic non-infectious diseases (CNIDs), considering sex differences.

Unlabelled: Material and Methods. A retrospective analysis of clinical and laboratory data of 760 patients with chronic non-communicable diseases (average age 52.

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.

Mutations in Fused in Sarcoma/Translocated in Liposarcoma (FUS) cause familial forms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by progressive axonal degeneration mainly affecting motor neurons. Evidence from transgenic mouse models suggests mutant forms of FUS exert an unknown gain-of-toxic function in motor neurons, but mechanisms underlying this effect remain unknown. Towards this end, we studied the effect of wild type FUS (FUS WT) and three ALS-linked variants (G230C, R521G and R495X) on fast axonal transport (FAT), a cellular process critical for appropriate maintenance of axonal connectivity.

Antiproton stopping power data for radiation therapy simulations.

Stopping powers of H, He, H, and HO targets for antiprotons have been calculated using a convergent close-coupling method. For He and H targets electron-electron correlations are fully accounted for using a multiconfiguration approximation. Two-electron processes are included using an independent-event model.

Target structure-induced suppression of the ionization cross section for low-energy antiproton-molecular hydrogen collisions: theoretical confirmation.

Theoretical confirmation of the experimentally observed phenomenon [Knudsen et al., Phys. Rev.

[Long-term quality of life of patients with postoperative ventral hernia].

125 patients with postoperative ventral hernia were included in the study. First group included patients who were operated on with the use of polypropylene mesh, second group of patients were operated on, using non-mesh techniques. Quality of life was assessed with the use of standard SF-36 questionnarie.