Anemia Diagnostic System Based on Impedance Measurement of Red Blood Cells.

Anemia is a condition in which red blood cells or the hemoglobin in the blood is lower than in healthy people. Red blood cells transport and supply oxygen needed to various organs in the human body. Anemia is caused by hypoxemia due to the lack of red blood cells and causes other serious health problems, such as heart problems, pregnancy complications, severe fatigue, or death.

Chimeric Antigen Receptor T Cells With Modified Interleukin-13 Preferentially Recognize IL13Rα2 and Suppress Malignant Glioma: A Preclinical Study.

Background: Interleukin-13 receptor α 2 (IL13Rα2) is a promising tumor-directed antigen of malignant glioma (MG). Here, we examine the efficacy and safety of T cells containing a YYB-103 chimeric antigen receptor (CAR) that can preferentially bind to IL13Rα2 on MG cells.

Methods: IL13 was modified on the extracellular domain by substitution of amino acids with E13K, R66D, S69D, and R109K and stably transfected into human T cells using a retroviral vector.

Practical Particulate Matter Sensing and Accurate Calibration System Using Low-Cost Commercial Sensors.

Air pollution is a social problem, because the harmful suspended materials can cause diseases and deaths to humans. Specifically, particulate matters (PM), a form of air pollution, can contribute to cardiovascular morbidity and lung diseases. Nowadays, humans are exposed to PM pollution everywhere because it occurs in both indoor and outdoor environments.

Practical Inter-Floor Noise Sensing System with Localization and Classification.

Inter-floor noise is a severe social problem which causes illegal arson, violence, and even murder. In this paper, an inter-floor noise sensing system is proposed to detect and record information related to inter-floor noise in an apartment building. The proposed system measured the noise level and estimated the direction of the noise source along with the type of noise.

Enhanced precision time synchronization for wireless sensor networks.

Time synchronization in wireless sensor networks (WSNs) is a fundamental issue for the coordination of distributed entities and events. Nondeterministic latency, which may decrease the accuracy and precision of time synchronization can occur at any point in the network layers. Specially, random back-off by channel contention leads to a large uncertainty.

The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells.

Cruciferous vegetables contain isothiocyanates including diindolylmethane (DIM) that exhibit cancer chemopreventive effects. We developed a series of synthetic ring-substituted DIM analogs including 5,5'-dibromoDIM that exhibited better inhibitory activity in breast and colon cancer cells than DIM. In this study, we investigated whether 5,5'-dibromoDIM inhibits the proliferation of KB and YD-10B oral squamous carcinoma cell lines.