Publications by authors named "Hyunseo Lim"
Adipose tissue, well known for its endocrine function, plays an immunological role in the body. The inflamed adipose tissue under LPS-induced systemic inflammation is characterized by the dominance of pro-inflammatory immune cells, particularly neutrophils. Although migration of macrophages toward damaged or dead adipocytes to form a crown-like structure in inflamed adipose tissue has been revealed, the neutrophilic interaction with adipocytes or the extracellular matrix remains unknown.
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- Corticosteroid therapy, particularly with dexamethasone, is commonly suggested for treating acute facial nerve weakness, but its effectiveness for traumatic injuries is debated.
- In a study with C57BL/6 mice, dexamethasone inhibited macrophage infiltration into facial nerves but slightly delayed overall functional recovery compared to a control group receiving saline.
- The results indicate that while dexamethasone can limit certain cellular responses after injury, further research is necessary to confirm its clinical benefits for treating traumatic facial nerve injuries.