Publications by authors named "Hyunjeong Kang"
Continuous and non-invasive measurement of intracranial pressure (ICP) in traumatic brain injury (TBI) is important to recognize increased ICP (IICP), which can reduce treatment delays. The purpose of this study was to develop an electroencephalogram (EEG)-based prediction model for IICP in a porcine TBI model. Thirty swine were anaesthetized and underwent IICP by inflating a Foley catheter in the intracranial space.
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- mTOR signaling, specifically through mTORC1 and mTORC2 complexes, is essential for neural development and is linked to various brain disorders, but upstream regulators of this signaling in neurons are not fully understood.
- This study highlights Tanc2, a neurodevelopmental adaptor protein, as a direct inhibitor of mTOR, with experiments showing that mice lacking Tanc2 exhibit severe developmental issues, while those with reduced Tanc2 levels show mTOR hyperactivity and related behavioral problems that can be reversed with the drug rapamycin.
- Tanc2 specifically inhibits mTOR in different stages of neuron development and in human neural progenitor cells, suggesting its significant role in regulating mTOR activity during neurodevelopment.
Photoplethysmograph (PPG) has been widely used to investigate various cardiovascular conditions. Previous studies demonstrated effects of temperature of the measurement environment; however, an integrated evaluation has not been established in environments with gradual air temperature variation. The purpose of this study is to investigate variations and relationships of blood pressure (BP), PPG and cardiovascular parameters such as heart rate (HR), stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR), by changing skin surface temperature (SST).
View Article and Find Full Text PDFUnlabelled: We report a hitherto not documented case of primary mucinous cystadenoma arising in the spermatic cord within the right inguinal canal of a78-year-old man. The tumor was painless, hard and mobile. A computed tomography scan on the pelvis revealed an oval shaped, low attenuation mass, measuring 5.
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