Publications by authors named "Hyung-Keun Cha"
: The mechanisms involved in the development of brain metastasis (BM) remain elusive. Here, we investigated whether BM is associated with spine involvement in patients with non-small-cell lung cancer (NSCLC). : A consecutive 902 patients with metastatic NSCLC were included from the Inha Lung Cancer Cohort.
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- - Current guidelines suggest starting NSCLC treatment with chemotherapy for patients with multiple metastases, avoiding whole-brain radiotherapy (WBRT) initially, even if there are brain metastases present.
- - This study analyzed the survival impact of WBRT combined with chemotherapy in NSCLC patients who were negative for EGFR, ALK, and PD-L1, had an ECOG performance status of 2, and exhibited multiple metastases, including in the brain.
- - Results revealed that patients receiving WBRT along with platinum-based chemotherapy had significantly better intracranial progression-free survival (iPFS) and overall survival (OS) compared to those who received chemotherapy alone, suggesting WBRT can improve outcomes in this patient group. *
Pulmonary mucormycosis is a relatively rare but often fatal opportunistic fungal infection that occurs mostly in immunocompromised patients. Endobronchial mucormycosis, a distinct clinical form of pulmonary mucormycosis, is very rare, and only a few cases have been reported. The most common bronchoscopic findings in patients with endobronchial mucormycosis are stenosis, erythematous mucosa and airway obstruction.
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