Evid Based Complement Alternat Med
August 2021
[This corrects the article DOI: 10.1155/2019/5160293.].
View Article and Find Full Text PDFEvid Based Complement Alternat Med
April 2019
Alzheimer's disease (AD) is linked to an extensive neuron loss via accumulation of amyloid-beta (A) as senile plaques associated with reactive astrocytes and microglial activation in the brain. The objective of this study was to assess the therapeutic effect of WS-5 ethanol extract in vitro and in vivo against A-induced AD in mice and to identify the extract's active constituents. In the present study, WS-5 exerted a significant inhibitory effect on acetylcholinesterase (AChE).
View Article and Find Full Text PDFBiomol Ther (Seoul)
November 2018
In order to discover lifespan-extending compounds made from natural resources, activity-guided fractionation of Roscoe (Zingiberaceae) ethanol extract was performed using the () model system. The compound 6-gingerol was isolated from the most active ethyl acetate soluble fraction, and showed potent longevity-promoting activity. It also elevated the survival rate of worms against stressful environment including thermal, osmotic, and oxidative conditions.
View Article and Find Full Text PDFA specific and reliable ultra-performance liquid chromatography-diode array detection method has been developed and validated for the quantitative assessment of a traditional Oriental herbal formulation, Samhwangsasim-tang (SST). A Halo reversed-phase amide column (2.7 µm, 4.
View Article and Find Full Text PDFThis study was performed to develop methods for the chromatographic determination of biomarkers in Hwangryunhaedok-tang (HHT) and the quantitative evaluation of commercial HHT. To develop an analytical method, an RP-amide column (2.7 μm, 4.
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