Publications by authors named "Hyung K Kang"

Objectives: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder, yet many cases remain undiagnosed. The STOP-Bang questionnaire was developed to identify individuals at high risk of OSA. We aimed to investigate the prevalence of individuals with suspected OSA using the STOP-Bang risk stratification in the general population of South Korea.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on older patients (≥80 years) undergoing femur fracture surgery, aiming to identify the incidence and risk factors for postoperative pulmonary complications.
  • Among the 479 patients analyzed, 11.7% experienced pulmonary complications, with pleural effusion, pneumonia, and atelectasis being the most prevalent issues, leading to longer hospital stays and higher mortality rates.
  • Key risk factors identified include age, chronic lung disease, Parkinson's disease, and other cardiovascular issues, emphasizing the need for focused care in this vulnerable population following surgery.
View Article and Find Full Text PDF
Article Synopsis
  • Chronic cough is a common problem, affecting about 9.6% of people worldwide, with more women than men experiencing it.
  • A study in South Korea looked at 625 adult patients to see how chronic cough differs between men and women based on age and causes.
  • Results showed that women were generally older, more often had asthma-related coughs, and even though the severity was similar, the prevalence of cough increased significantly in women as they got older.
View Article and Find Full Text PDF
Article Synopsis
  • Lymphangioleiomyomatosis (LAM) is a rare disorder marked by the growth of abnormal smooth muscle-like cells, and the effectiveness of serum VEGF-D as a diagnostic tool in Korean patients needs evaluation.
  • This study collected serum samples from 40 LAM patients and 24 controls to measure VEGF-D levels and analyze its diagnostic potential using ROC curve analysis.
  • Results indicated that serum VEGF-D levels were significantly elevated in LAM patients, showing strong predictive value for diagnosis, making it a potentially useful biomarker for this condition in the Korean population.
View Article and Find Full Text PDF

The objective of this investigation was to formulate a model for predicting intracranial pressure (ICP) by utilizing optic nerve sheath diameter (ONSD) during endovascular treatment for an aneurysmal subarachnoid hemorrhage (aSAH), incorporating explainable predictive modeling. ONSD measurements were conducted using a handheld ultrasonography device during the course of endovascular treatment ( = 126, mean age 58.82 ± 14.

View Article and Find Full Text PDF

Background: Mechanical power (MP) has been reported to be associated with clinical outcomes. Because the original MP equation is derived from paralyzed patients under volume-controlled ventilation, its application in practice could be limited in patients receiving pressure-controlled ventilation (PCV). Recently, a simplified equation for patients under PCV was developed.

View Article and Find Full Text PDF

Introduction: Concurrent obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are referred to as COPD-OSA overlap. We investigated the prevalence and clinical significance of COPD-OSA overlap in the general population of South Korea.

Methods: Data were obtained from the 2019 Korea National Health and Nutrition Examination Survey.

View Article and Find Full Text PDF

Interstitial lung diseases (ILDs) are a diverse collection of lung disorders sharing similar features, such as inflammation and fibrosis. The diagnosis and management of ILD require a multidisciplinary approach using clinical, radiological, and pathological evaluation. Progressive pulmonary fibrosis (PPF) is a distinct form of progressive and fibrotic disease, occurring in ILD cases other than in idiopathic pulmonary fibrosis (IPF).

View Article and Find Full Text PDF
Article Synopsis
  • The study, conducted by the Center for Personalized Precision Medicine of Tuberculosis (cPMTb), aims to create personalized treatment systems for tuberculosis (TB) and to compare patients with TB, non-tuberculosis mycobacterial infection (NTM), and latent TB infection (LTBI).
  • A total of 1,226 patients were analyzed, revealing that TB patients were generally older, had lower body mass index (BMI), and higher diabetes rates compared to those with LTBI, while patients with NTM had a higher female proportion and a history of TB.
  • The analysis of genetic traits showed similar distributions of N-acetyltransferase-2 (NAT2) and SLCO
View Article and Find Full Text PDF

Background: Endobronchial ultrasound (EBUS) is widely used to diagnose lung cancer. Monitored anesthesia care (MAC) can enhance patient comfort and procedural conditions during EBUS. EBUS under MAC is usually safe but can lead to various complications.

View Article and Find Full Text PDF

Background: Few studies have comprehensively evaluated the risk of lung cancer in tuberculosis survivors with consideration of smoking status and chronic obstructive pulmonary disease (COPD). Furthermore, little is known about lung cancer risk factors in tuberculosis survivors.

Methods: This population-based cohort study enrolled tuberculosis survivors (n = 75 467) between 2010 and 2017 and 1:1 age- and sex-matched controls.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to create machine-learning models that use CT scans and clinical data to predict respiratory outcomes in COVID-19 patients, focusing on pneumonia, hypoxia, and respiratory failure.
  • A total of 387 patients were analyzed, revealing that 50.4% developed pneumonia, while 22% experienced hypoxia and 4.9% faced respiratory failure; several clinical factors, including vaccination status and laboratory results, were identified as significant predictors.
  • The models demonstrated high predictive accuracy, with area under the receiver operating characteristic curve (AUC) values of 0.904 for pneumonia, 0.890 for hypoxia, and 0.969 for respiratory failure, indicating their reliability in clinical settings.
View Article and Find Full Text PDF
Article Synopsis
  • Recent reports indicate that pneumonitis may be a rare complication following SARS-CoV-2 vaccinations, with this study aiming to clarify its clinical features and outcomes.
  • A nationwide survey identified 49 cases of vaccine-associated pneumonitis, with most patients being male and a median age of 66 years; symptoms typically manifested within 5 days post-vaccination.
  • Although many patients saw improvement with corticosteroid treatment, 20% experienced worsening symptoms, and there was an observed mortality rate of 17%.
View Article and Find Full Text PDF

Background: Chronic cough is a heterogeneous disease with various aetiologies that are difficult to determine. Our study aimed to categorise the phenotypes of chronic cough.

Methods: Adult patients with chronic cough were assessed based on the characteristics and severity of their cough using the COugh Assessment Test (COAT) and the Korean version of the Leicester Cough Questionnaire.

View Article and Find Full Text PDF

Background: Subjects with diabetes are at higher risk of serious influenza-related complications. We aimed to investigate the yearly trend of influenza vaccination and factors associated with being unvaccinated for influenza in subjects with diabetes using a nationwide observational study performed within the recent decade.

Methods: Among 105,732 subjects from the Korea National Health and Nutrition Examination Survey between 2007 and 2019, 8,632 with diabetes were included.

View Article and Find Full Text PDF

Diffuse alveolar haemorrhage (DAH) is a life-threatening condition caused by widespread damage to the small pulmonary vessels. Common chest imaging findings in patients with DAH show bilateral diffuse airspace opacities. DAH complicating antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, including microscopic polyangiitis, should be considered as a differential diagnosis in patients with progressive dyspnea, reduced haemoglobin levels, and alveolar opacities on chest imaging.

View Article and Find Full Text PDF

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease (ILD) with variable and heterogeneous clinical course. The GAP (gender, age, and physiology) model had been used to predict mortality in patients with IPF, but does not contain exercise capacity. Therefore, our aim in this study was to develop new prognostic scoring system in the Korea IPF Cohort (KICO) registry.

View Article and Find Full Text PDF

Purpose: Although the coexistence of asthma and bronchiectasis is common, the impacts of asthma on bronchiectastic patients (BE) have not been well evaluated because this issue using bronchiectasis cohorts has been investigated in only a few studies.

Methods: In the present study, 598 patients who were prospectively enrolled in the Korean bronchiectasis registry were evaluated. The clinical characteristics between BE with asthma and those without asthma were compared.

View Article and Find Full Text PDF

A 62-year-old man who presented with complaints of cough and hemoptysis was found to have an endobronchial tumor which obstructed the lingular bronchus. Histopathologic examination of a bronchoscopic biopsy of the tumor was consistent with malignant melanoma. Skin, mucosal, and eye examinations failed to detect the primary site of melanoma and the patient was diagnosed with endobronchial melanoma of unknown primary (MUP).

View Article and Find Full Text PDF

Regdanvimab is the only monoclonal antibody available in Korea that targets severe acute respiratory syndrome coronavirus 2. We retrospectively evaluated the clinical characteristics of 374 adults hospitalized with coronavirus disease 2019 (COVID-19) who were treated with regdanvimab from September through December 2021. In total, 322 (86.

View Article and Find Full Text PDF

Background: Gastroesophageal reflux disease (GERD) is a common comorbidity of nontuberculous mycobacteria (NTM) pulmonary disease (PD). Although GERD is associated with more symptoms and severe disease in patients with NTM PD, whether GERD is associated with an increased risk of NTM PD developing is unknown.

Research Question: Does GERD influence the development of NTM PD? Are there any factors associated with an increased risk of NTM PD among patients with GERD? What is the impact of NTM PD on the health-care use of patients with GERD?

Study Design And Methods: Data from the Korean National Health Insurance Service National Sample Cohort between 2002 and 2015 were used.

View Article and Find Full Text PDF

Background: Patients with non-cystic fibrosis bronchiectasis have an increased risk of lung cancer, followed by higher mortality in this population. Because the risk factors of lung cancer have not been well identified, this study aimed to investigate the risk factors of lung cancer in individuals with newly diagnosed bronchiectasis.

Methods: This cohort study using the Korean National Health Insurance Service database identified 7425 individuals with incident bronchiectasis among those who participated in the health screening exam in 2009.

View Article and Find Full Text PDF

Background: Chest computed tomography (CT) scans play an important role in the diagnosis of coronavirus disease 2019 (COVID-19). This study aimed to describe the quantitative CT parameters in COVID-19 patients according to disease severity and build decision trees for predicting respiratory outcomes using the quantitative CT parameters.

Methods: Patients hospitalized for COVID-19 were classified based on the level of disease severity: (1) no pneumonia or hypoxia, (2) pneumonia without hypoxia, (3) hypoxia without respiratory failure, and (4) respiratory failure.

View Article and Find Full Text PDF

Smoking traditionally has not been considered as a cause of bronchiectasis. However, few studies have evaluated the association between smoking and bronchiectasis. This study aimed to investigate the association between smoking status and bronchiectasis development in young adults.

View Article and Find Full Text PDF