Perceived social position, active engagement with life, and depressive symptoms among older adults.

Rationale: Despite the existing literature on the relationship between perceived social position (PSP) and depressive symptoms, there remain gaps in our understanding, particularly regarding the potential for asymmetric effects of increases and decreases in PSP and the underlying mechanisms involved.

Objective: This study aims to examine whether increases and decreases in PSP are differentially associated with depressive symptoms and to explore the potential mediating role of active engagement with life in these associations.

Methods: This study utilized data from the Korean Longitudinal Study of Aging (KLoSA), collected between 2008 and 2018, involving a sample of 3506 individuals aged 65 or older.

A longitudinal study of immigrant mothers' destination-language proficiency and their children's psychological well-being: Evidence and mechanisms from a study in South Korea.

Rationale: Despite the well-established link between an immigrant's destination-language proficiency and psychological well-being, little is known about the relationship between an immigrant's destination-language proficiency and well-being of their children.

Objective: This study investigated whether and how immigrant mothers' Korean proficiency is associated with life satisfaction and depressive symptoms among their children in South Korea. A comprehensive set of potential underlying mechanisms was also examined.

The use of assistive devices and social engagement among older adults: heterogeneity by type of social engagement and gender.

Little is known about the relationship between the use of assistive devices for functional loss and social engagement. This study investigated whether wearing assistive devices (dentures and hearing aids) is associated with social engagement among older adults in South Korea. Potential heterogeneity by type of social engagement (informal social contact versus formal social activity) and gender was also examined.

Homeownership and Psychological Resources Among Older Adults: Do Gender and Mortgage Status Moderate Homeownership Effects?

This study examined whether homeownership is associated with life satisfaction and depressive symptoms among older adults aged 65 or over and whether these associations differ by gender. This study further distinguished mortgagors from owner-occupiers. Using six waves of the Korean Longitudinal Study of Ageing ( = 3540), we used generalized estimating equations as well as random- and fixed-effects regression analyses.

Asn-Linked Glycosylation Contributes to Surface Expression and Voltage-Dependent Gating of Cav1.2 Ca²⁺ Channel.

The Cav1.2 Ca2+ channel is essential for cardiac and smooth muscle contractility and many physiological functions. We mutated single, double, and quadruple sites of the four potential Asn (N)-glycosylation sites in the rabbit Cav1.

Asp residues of the Glu-Glu-Asp-Asp pore filter contribute to ion permeation and selectivity of the Ca(v)3.2 T-type channel.

Voltage-activated Ca2+ channels are membrane protein machinery performing selective permeation of external calcium ions. The main Ca2+ selective filters of all high-voltage-activated Ca2+ channel isoforms are commonly composed of four Glu residues (EEEE), while those of low-voltage-activated T-type Ca2+ channel isoforms are made up of two Glu and two Asp residues (EEDD). We here investigate how the Asp residues at the pore loops of domains III and IV affect biophysical properties of the Ca(v)3.