Publications by authors named "Hyun-Wu Yoon"
Pain Res Manag
March 2021
Article Synopsis
- Mannitol was found to enhance the pain relief effects of diphenhydramine, a potential alternative local anesthetic, in a study using male Sprague-Dawley rats.
- When injected subcutaneously, both 0.5% and 1% diphenhydramine significantly reduced pain response times compared to a control treatment, with effects lasting over 30 minutes.
- The combination of 1% diphenhydramine with 0.5 M mannitol produced a significant improvement in pain relief compared to diphenhydramine alone, while the addition of epinephrine did not enhance the effectiveness of diphenhydramine.
