Publications by authors named "Hyun-Ju Min"
Article Synopsis
- A study was conducted to evaluate how effective rapid response team (RRT) nurses’ subjective bedside assessments are in predicting short-term patient deterioration compared to established scoring systems.
- The research included 1,426 patients, where less than 20% experienced mortality or intensive care unit admission within a day, and the performance of the nurses’ assessments was compared using various early warning scores.
- The bedside assessment tool, Patient Acuity Rating (PAR), had a higher predictive accuracy (area under the curve of 0.87) compared to other scoring methods, indicating it can be a valuable tool for RRT nurses in assessing patient prognosis.
Introduction: This study aimed to determine the occurrence rate and risk factors of cardiopulmonary arrest (CPA) during intra-hospital transport (IHT) among critically ill patients, accompanied by a rapid response team (RRT).
Methods: We performed a retrospective cohort study in a 1300-bed tertiary-care teaching hospital. Data of all admitted patients transported within the hospital and accompanied by the RRT from October 2012 to May 2016 were included.
Background: Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites caused by liver cirrhosis is limited. The aims of our study were to investigate the usefulness of ascitic fluid lactoferrin levels for the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and to evaluate the association between lactoferrin levels and the development of hepatocellular carcinoma (HCC).
Methods: A total of 102 patients with ascites caused by cirrhosis were consecutively enrolled into the study, from December 2008 to December 2011.
Article Synopsis
- * Overall, HCV infection rates among adults rose from 0.14% to 0.18% during the period, with the highest rates found in Busan, Jeonnam, and Gyeongnam, particularly noted in specific towns like Jindo and Namhae.
- * Findings indicate regional disparities in HCV prevalence, suggesting the need for targeted prevention strategies and enhanced surveillance in high-risk areas to curb future infections.
Background/aims: The prevalence of hepatitis C virus (HCV) infection in Busan, Gyeongnam, and Jeonnam Provinces in Korea is more than twice the national average. This study aimed to examine whether demographic and lifestyle characteristics are associated with HCV infection in these areas.
Methods: A case control study was performed at three study hospitals.
An ectopic opening of the common bile duct (CBD) into the duodenal bulb is a very rare congenital anomaly of the biliary system, which may cause recurrent duodenal ulcer or biliary diseases such as choledocholithiasis and cholangitis. Endoscopic retrograde cholangiopancreatography (ERCP) plays a major role in the diagnosis of this anomaly. We report two such cases: one in a 61-year-old man and the other in a 57-year-old man.
View Article and Find Full Text PDF[Clinicopathological characteristics and prognosis of alpha-fetoprotein producing gastric cancer].
Korean J Gastroenterol
December 2013
Background/aims: Several studies reported a subgroup of gastric cancer patients showing elevated serum alpha-fetoprotein (AFP) at the time of diagnosis. We investigated the clinicopathological characteristics and prognostic factors of AFP producing gastric cancer (AFPPGC) by comparing with AFP non-producing gastric cancer (AFPNPGC).
Methods: A total of 909 patients were diagnosed with gastric cancer from January 2005 to March 2013 at Gyeongsang National University Hospital and their AFP levels were measured at the time of diagnosis.
Genotype-4 hepatitis E in a human after ingesting roe deer meat in South Korea.
Clin Mol Hepatol
September 2013
Article Synopsis
- * A 43-year-old man in South Korea was diagnosed with acute HEV after experiencing abdominal issues and jaundice following the consumption of raw roe deer meat 6-8 weeks prior.
- * Genetic analysis confirmed the presence of genotype-4 HEV, suggesting that eating wild game like deer can lead to zoonotic transmission of the virus.
We encountered an indigenous case of intestinal capillariasis with protein-losing enteropathy in the Republic of Korea. A 37-year-old man, residing in Sacheon-si, Gyeongsangnam-do, admitted to the Gyeongsang National University Hospital (GNUH) due to long-lasting diarrhea, abdominal pain, anasarca, and weight loss. He recalled that he frequently ate raw fish, especially the common blackish goby (Acanthogobius flavimanus) and has never been abroad.
View Article and Find Full Text PDFArticle Synopsis
- - The study explored autoimmune hepatitis (AIH), a rare liver disease, by analyzing data from 343 adult patients in Korea diagnosed between 2005 and 2009, noting a predominance of females and a mean age of 52.8 years.
- - Patients displayed various symptoms at diagnosis, with 30.6% being asymptomatic, and diagnostic criteria revealed differences in categorizations of AIH between revised original and simplified criteria.
- - The results indicated that while type I AIH is prevalent in Korea, the two diagnostic criteria showed low concordance and modest sensitivity, necessitating additional research for validation of these criteria.
Article Synopsis
- A study investigated the hepatotoxic effects of the herbal supplement Polygonum multiflorum Thunb in 25 patients diagnosed with toxic hepatitis after consuming the product.
- The patients, predominantly middle-aged, displayed symptoms like jaundice, and the majority showed signs of liver injury confirmed through clinical evaluations and liver biopsies.
- Most patients recovered with supportive care, though one required a liver transplant and another died from liver failure, highlighting the serious risks associated with this herbal preparation.
The synchronous prevalence of colorectal neoplasms in patients with stomach cancer.
J Korean Soc Coloproctol
October 2011
Article Synopsis
- - The study aimed to explore the link between stomach cancer and colorectal cancer by analyzing the prevalence of colorectal neoplasms in patients with stomach cancer compared to those without.
- - It evaluated 123 stomach cancer patients and 246 matched controls, finding a significantly higher colorectal neoplasm rate of 35.8% in stomach cancer patients versus 17.9% in controls (P < 0.001).
- - The conclusion suggests that individuals with stomach cancer are at a higher risk for colorectal neoplasms, particularly those over 50, indicating the need for routine colonoscopy screenings in these patients.
Background/aims: This study investigated the clinical features and prognosis of primary biliary cirrhosis (PBC) in Korea.
Methods: Clinical data of patients diagnosed as PBC between 1997 and 2008 at eight referral hospitals were analyzed retrospectively. PBC was diagnosed based on liver function tests, presence of serum antimitochondrial antibody (AMA), and histopathological findings.
Article Synopsis
- Alveolar soft part sarcoma (ASPS) is a rare soft tissue cancer mainly affecting young people and has a generally poor prognosis due to likely metastases.
- *Despite being slow-growing, ASPS often spreads to organs like the lung, brain, and bone, with gastrointestinal metastasis being very uncommon.
- *This report highlights a unique case where ASPS caused serious complications like upper gastrointestinal bleeding and jejunal intussusception due to rare metastatic spread to the digestive tract.
Article Synopsis
- - A 60-year-old male with chronic hepatitis C and liver cirrhosis experienced sudden-onset hearing loss while undergoing combination therapy with pegylated interferon alpha and ribavirin, which is generally associated with various side effects but rarely hearing loss.
- - The patient had previously been treated with conventional interferon and ribavirin for a year, but relapsed six months post-treatment and started a new regimen with pegylated interferon-2b and ribavirin.
- - Following the onset of right-sided hearing loss and tinnitus, the patient discontinued the medication and was prescribed prednisone, leading to almost complete recovery of his hearing after 10 days.
Article Synopsis
- Several cases of hepatitis induced by the herb Polygonum multiflorum Thunb have been reported globally, with its active ingredient anthraquinone believed to contribute to liver damage.
- A 34-year-old Korean man, previously healthy, developed hepatitis and reactivated pulmonary tuberculosis after consuming this herb in liquor and tea for a month, leading to fatigue and jaundice.
- His condition improved after stopping the herb, but he experienced bone marrow suppression and exhibited symptoms of tuberculosis, which were treated successfully, highlighting the dual risk of liver and bone marrow issues linked to P. multiflorum Thunb.
Article Synopsis
- A rare case of a primary benign schwannoma in the liver was reported, marking the first such case in Korea, with only nine total cases documented worldwide.
- A 36-year-old woman experienced vague epigastric pain, leading to imaging tests that revealed a multi-septated cystic mass in her liver.
- The mass was surgically removed and identified as a 5 x 4 x 2 cm mass filled with reddish yellow fluid, confirmed to be a benign schwannoma through histological examination and specific immunoreactions.
Article Synopsis
- Biliary duct injuries often occur due to surgical procedures for gallbladder stones, but can also be caused by blunt abdominal trauma, like in car accidents.
- This study highlights a specific case of a suprapancreatic biliary stricture that resulted from a mesenteric tear after a road traffic incident.
- Successful endoscopic stent placement was performed to relieve the biliary stricture in this case.
Article Synopsis
- Recent studies show changes in neural and epithelial cadherin (E-cadherin) expression in various epithelial tumors, but its significance in hepatocellular carcinoma (HCC) is unclear.
- This study analyzed cadherin expression in tumor and adjacent non-tumor tissues from 52 HCC patients who underwent surgery, examining how these patterns relate to clinical outcomes.
- High levels of neural cadherin (N-cadherin) were linked to a higher recurrence rate of tumors within 2 years post-surgery, making it a potential predictive marker for early recurrence in HCC cases.
Article Synopsis
- - Preoperative portal vein embolization (PVE) increases the future liver remnant (FLR) volume, allowing for successful surgical resection in patients with small FLR, but its impact on survival in hepatocellular carcinoma (HCC) was uncertain.
- - A study involving 32 HCC patients showed that following PVE, FLR volume significantly increased, and there was no mortality from PVE or surgery, with a notable improvement in the 5-year survival rate of those treated with PVE compared to those treated with transarterial chemoembolization (TACE).
- - The results indicated that patients who underwent PVE had a 5-year survival rate of 71.9%, significantly higher than the 45
[The clinical study on spontaneously ruptured hepatocellular carcinoma].
Korean J Gastroenterol
September 2004
Article Synopsis
- Spontaneous rupture of hepatocellular carcinoma (HCC) is a rare but serious condition that can lead to significant internal bleeding, with incidences between 10.2% to 14.5% in high-prevalence areas.
- A study of 642 HCC patients identified 83 cases of spontaneous rupture (12.9%), analyzing their medical records to uncover risk factors and treatment outcomes.
- Key findings indicated that advanced Child-Pugh class and Okuda stage, along with tumor location, were risk factors for rupture, while successful treatment through transarterial embolization (TAE) led to improved survival rates compared to just supportive care.