Bis-spirolabdane-type diterpenoids from Leonurus sibiricus.

Six new bis-spirolabdane-type diterpenoids, leosibirinone A (1), 3alpha-acetoxyleoheteronone C (2), leosibirinone B (3), 3alpha-hydroxyleoheteronone A (4), 3alpha-acetoxyleoheteronone E (5), and 3alpha-acetoxy-15-epileoheteronone E (6), were isolated from the aerial parts of Leonurus sibiricus. Their structures were identified on the basis of 1D and 2D NMR, including (1)H-(1)H COSY, HSQC, HMBC, and NOESY spectroscopic analyses.

Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts.

The methanol extract from Selaginella tamariscina significantly inhibited UV irradiation induced activity of matrix metalloproteinase-1 (MMP-1) in primary fibroblasts from human skin. Using the technique of bioassay-directed chromatographic separation, five biflavonoids were isolated from the ethyl acetate soluble fraction of S. tamariscina.

A new lignan glycoside from the stem bark of Styrax japonica S. et Z.

A new lignan glycoside was isolated from the stem bark of Styrax japonica (Styracaceae). This lignan glycoside, named styraxjaponoside C (1), was identified by spectroscopic methods. In addition, six known compounds, arctiin (2), pinoresinol-4-O-beta-D-glucopyranoside (3), matairesinoside (4), methylsyringin (5), syringin (6), and egonol (7) were isolated from this plant.