Publications by authors named "Hyun Tae Ryu"
Background: Fractional exhaled nitric oxide (FeNO) is useful in the management of asthma and predicting the efficacy of standard corticosteroids and biologics. However, the diagnostic value of FeNO in asthmatic chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear.
Objective: We assessed FeNO levels in patients with CRSwNP and evaluated the diagnostic value of FeNO for screening type 2 CRSwNP (T2-CRSwNP) with asthma.
Article Synopsis
- The study explored the role of neutrophil extracellular traps (NET) and eosinophil extracellular traps (EET) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) to understand treatment resistance.
- Researchers analyzed nasal polyp specimens from 117 patients and categorized them based on levels of extracellular trap formation, finding significant differences in eosinophil and NET counts between refractory and non-refractory cases.
- The findings indicate that tissue eosinophilia and EETosis could serve as important prognostic indicators for CRSwNP, with NETosis being a useful biomarker in cases with neutrophilic inflammation.
Objective: The recurrence of chronic rhinosinusitis (CRS) after functional endoscopic sinus surgery (FESS) is influenced by various factors, potentially including the endotype based on the molecular pathophysiology of CRS. This study investigated differences in the recurrence pattern of CRS by endotype after primary FESS.
Methods: This retrospective study enrolled patients who had undergone revision FESS for recurrent CRS.