Current issues and areas for improvement in the Korean Dental Hygienist National Licensing Examination: an expert Delphi survey among dental hygienists.

Purpose: This study aimed to investigate current issues and areas for improvement in the Korean Dental Hygienist National Licensing Examination (KDHNLE) through an expert Delphi survey.

Methods: A Delphi survey was conducted from May through August 2016 in Korea. This Delphi survey included 20 persons representing the field of dental hygiene (7 groups from various dental hygiene-related organizations).

Subject-Object Asymmetry in the Second Language Acquisition of English Relatives and Embedded Wh-Questions.

This study examined subject-object asymmetry and developmental sequence in the second language (L2) acquisition of three types of wh-extraction, i.e., English headed relatives, headless relatives, and embedded wh-questions.

STAT1 drives tumor progression in serous papillary endometrial cancer.

Recent studies of the interferon-induced transcription factor STAT1 have associated its dysregulation with poor prognosis in some cancers, but its mechanistic contributions are not well defined. In this study, we report that the STAT1 pathway is constitutively upregulated in type II endometrial cancers. STAT1 pathway alteration was especially prominent in serous papillary endometrial cancers (SPEC) that are refractive to therapy.

Characterizations of Shell and Mantle Edge Pigmentation of a Pacific Oyster, Crassostrea gigas, in Korean Peninsula.

The objectives of this study were to investigate color patterns of shell and mantle edge pigmentation of a Pacific oyster, C. gigas, and to estimate variance components of the two colors. A sample of 240 F0 oysters was collected from six aquaculture farms in Tongyeong, Korea to measure shell color and mantle edge pigmentation.

A Web-based health promotion program for patients with metabolic syndrome.

Purpose: The population of metabolic syndrome is increasing in Korea. The prevalence is related to lifestyle, such as lack of physical activity and irregular diet. Most patients with metabolic syndrome know that lifestyle intervention is important to managing the condition.

Menstrual cyclic change of metastin/GPR54 in endometrium.

Metastin/kisspeptin is encoded by KISS1 and functions as an endogenous ligand of GPR54. Interaction of metastin with GPR54 suppresses metastasis and also regulates release of gonadotropin-releasing hormone, which promotes secretion of estradiol (E2) and progesterone (P4). We have previously demonstrated epigenetic regulation of GPR54 in endometrial cancer and the potent role of metastin peptides in inhibiting metastasis in endometrial cancer.

Isolation and characterization of novel microsatellite markers for the northern mauxia shrimp, Acetes chinensis, using pyrosequencing.

Among the 14 species in the Acetes genus, Acetes japonicus and Acetes chinensis, are the only and also abundant two species around the Korean Peninsula, and are used in traditional recipes. These species are of great economic importance, but little is known about their population genetics, despite the fact that information of this kind is important for stock assessment, fisheries management and identification of origin. A total of 9 microsatellite (MS) markers for A.

Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers.

Endometrial cancer, one of the most common gynecologic malignancies, is increasing in Japan, nearly doubling over the last decade. High-grade disease patients are often resistant to conventional chemotherapy with platinum agents; therefore, discovery of efficacious new drugs in this setting is required to benefit chemorefractory cases. The 50% growth-inhibitory (GI50) concentration of 27 clinically relevant drugs was measured in the NCI60 panel of cell lines.

Job analysis of clinical research coordinators using the DACUM process.

Purpose: This study was done to analyze the job of clinical research coordinators (CRCs).

Methods: Through the "developing a curriculum (DACUM)" workshop, the definition of CRCs' role was described and CRCs' duties and tasks were identified. Finally, the developed duties and tasks were validated for importance, difficulty, and frequency.

[Effects of a home-based exercise program for patients with stomach cancer receiving oral chemotherapy after surgery].

Purpose: The purpose of this study was to identify the effects of a home based exercise program for patients with stomach cancer who were undergoing oral chemotherapy.

Methods: The home-based exercise program was developed from the study findings of Winningham (1990) and data from the Korea Athletic Promotion Association (2007). The home-based exercise program consisted of 8 weeks of individual exercise education and exercise adherence strategy.

The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer.

Peritoneal dissemination including omental metastasis is the most frequent route of metastasis and an important prognostic factor in advanced ovarian cancer. We analyzed the publicly available microarray dataset (GSE2109) using binary regression and found that the transforming growth factor (TGF)-beta signaling pathway was activated in omental metastases as compared to primary sites of disease. Immunohistochemical analysis of TGF-beta receptor type 2 and phosphorylated SMAD2 indicated that both were upregulated in omental metastases as compared to primary disease sites.

[Evaluation of the Korean formal educational program for training care workers for frail elderly].

Purpose: This study was done to evaluate the formal education program provided by the Korean government for care workers for frail elderly people.

Methods: This study was a cross-sectional survey in which 438 certified care workers who had completed the education program participated. Data were collected from June to October 2009, using a self-report questionnaire consisting of satisfaction with, and understanding of the education program.

Analysis of mutations and the association between polymorphisms in the cerebral dopamine neurotrophic factor (CDNF) gene and Parkinson disease.

Neurotrophic factors support the survival of dopaminergic neurons. The cerebral dopamine neurotrophic factor (CDNF) is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). To investigate whether rare or common variants in CDNF are associated with Parkinson disease (PD), we performed mutation analysis of CDNF and a genetic association study between CDNF polymorphisms and PD.

Endometrial cancer implanted within a cesarean section scar.

Several reports have documented adenocarcinoma arising from endometriotic implants within cesarean section (C-S) scars on the serosal surface of the uterus; however, endometrial cancer invading the C-S scar from the uterine cavity has not been described. We report a case of a grade 1 endometrioid adenocarcinoma 'drop' lesion invading a previous C-S scar with resultant cervical stromal invasion. Using both MR images and a thorough review of the pathology, the tumor at the C-S scar was determined to be an implant derived from a primary lesion at the uterine fundus.

GPR54 is a target for suppression of metastasis in endometrial cancer.

Invasion into deep myometrium and/or lymphovascular space is a well-known risk factor for endometrial cancer metastasis, resulting in poor prognosis. It is therefore clinically important to identify novel molecules that suppress tumor invasion. Reduced expression of the metastasis suppressor, kisspeptin (KISS1), and its endogenous receptor, GPR54, has been reported in several cancers, but the significance of the KISS1/GPR54 axis in endometrial cancer metastasis has not been clarified.

Evaluation of the completeness of the nursing process for patients having gastrectomy using electronic nursing records.

The purpose of this study was to evaluate recording completeness of the nursing process. We compared nursing statements documented at the time when the Electronic Nursing Record (ENR) system, based on the ICNP, was implemented in 2004 with those documented in 2007. The ENRs for 35 gastrectomy patients in each year were selected for evaluation.

Effects of Meridian acupressure for stroke patients in Korea.

Aim: To examine the effects of Meridian acupressure on the functions of affected upper extremities, activity of daily living and depression for stroke patients.

Background: The handicaps of stroke patients necessitate multidisciplinary rehabilitation, which is aimed at decreasing the consequences of the illness in daily functions. In traditional Chinese medicine, Meridian acupressure has been used for rehabilitation of affected upper extremities of hemiplegia stroke patients in clinical practice.

[Development of a multimedia learning DM diet education program using standardized patients and analysis of its effects on clinical competency and learning satisfaction for nursing students].

Purpose: The purpose of this study was to develop a multimedia learning program for patients with diabetes mellitus (DM) diet education using standardized patients and to examine the effects of the program on educational skills, communication skills, DM diet knowledge and learning satisfaction.

Methods: The study employed a randomized control posttest non-synchronized design. The participants were 108 third year nursing students (52 experimental group, 56 control group) at K university in Seoul, Korea.

The effects of a weight loss program focusing on maternal education on childhood obesity.

Purpose: Childhood obesity is a matter of great concern because of its negative health and social consequences. We examined the effect of a weight control program focusing on maternal education on childhood obesity, given that the incidence of obesity is greatly affected by parents.

Methods: A two-group pre-test/post-test design was used.

Aquatic exercise in older Korean women with arthritis: identifying barriers to and facilitators of long-term adherence.

The purpose of this study was to identify factors influencing long-term adherence to aquatic exercise in older women with arthritis. Participants (n = 72) completed an educational program on aquatic exercise and underwent follow up for 6 months. At follow-up, women who continued aquatic exercise (adherence group, n = 25) had significantly higher scores than women in the nonadherence group (n = 47) in exercise self-efficacy (p < 0.

[Influencing factors for fatigue in cancer patients].

Purpose: The purpose of this study was to identify degrees of fatigue and influencing factors for fatigue in cancer patients.

Method: Data was collected by questionnaires from 115 cancer patients at 3 hospitals in Seoul. The research instruments utilized in this study were fatigue, physical symptoms, depression, family support, and health promoting behaviors.

[Effects of a self-help group program for young adults with hemophilia].

Purpose: The purpose of this study was to identify the effects of Self-help program for Young adults with hemophilia.

Method: A quasi-experimental design was used. The subjects were 40 young adults with hemophilia, 21 in the experimental group and 19 in the control group.

[Effect of East-West Self-help Group program for rehabilitation of post stroke clients].

Purpose: The purpose of this study was to evaluate the effect of an East-West Self-help program for Rehabilitation of post-stroke patients.

Method: A quasi-experimental design was used. The subjects were 75 post stroke clients(Exp.

[Psychosocial adjustment of young adult to hemophilia: living like a normal person].

Purpose: To explore how young adults in their 20s adjust to hemophilia.

Method: Grounded theory method guided the data collection and analysis. A purposeful sample of 15 young adults with hemophilia participated during the period of 2000-2001.

[Adjustment patterns of illness process of people with hemophilia in Korea].

Purpose: The purpose of this study was to explore adjustment pattern of illness process of people with hemophilia in Korea.

Method: 23 people with hemophilia had participated for this study. The data were collected through in-depth interviews and analyzed using Strauss & Corbin's grounded theory method.