Risk factors for middle ear cholesteatoma surgery based on Korean population data.

Background: Studies of risk factors for middle ear cholesteatoma surgery using population-based data are lacking.

Objectives: To investigate the risk factors for cholesteatoma surgery in adults based on population data from Korea.

Materials And Methods: For this retrospective study, we used Korean National Health Insurance Service National Sample Cohort data.

Seasonal variation in peripheral vestibular disorders based on Korean population data.

Objectives: Comprehensive studies in which the seasonal variation in peripheral vestibular disorders was evaluated using data from an entire population are insufficient. The seasonal variation in peripheral vestibular disorders based on data from the entire Korean population was investigated in the present study.

Methods: Retrospective data from the National Health Insurance Service of Korea from 2008 to 2020 was analyzed.

Risk for depression and anxiety in patients with facial palsy based on population-based data from Korea.

Background: Several studies point out the association of facial palsy with psychiatric distress such as depression and anxiety. However, there have been few studies on this association based on population-based data.

Objectives: To investigate the risk for depression and anxiety disorders in patients with Bell's palsy and in those with Ramsay Hunt syndrome.

Snoring might be a warning sign for metabolic syndrome in nonobese Korean women.

Metabolic syndrome (MetS) is an underlying cause of various diseases and is strongly associated with mortality. In particular, it has been steadily increasing along with changes in diet and lifestyle habits. The close relationship between sleep apnea and MetS is well established.

Single-cell RNA sequencing identifies distinct transcriptomic signatures between PMA/ionomycin- and αCD3/αCD28-activated primary human T cells.

Immunologists have activated T cells in vitro using various stimulation methods, including phorbol myristate acetate (PMA)/ionomycin and αCD3/αCD28 agonistic antibodies. PMA stimulates protein kinase C, activating nuclear factor-κB, and ionomycin increases intracellular calcium levels, resulting in activation of nuclear factor of activated T cell. In contrast, αCD3/αCD28 agonistic antibodies activate T cells through ZAP-70, which phosphorylates linker for activation of T cell and SH2-domain-containing leukocyte protein of 76 kD.

Association between hearing loss and trauma based on population data of Korea.

Background: Although several studies have been conducted to assess the association between hearing loss (HL) and trauma, no studies have analyzed trauma comprehensively based on population-based data.

Objectives: To investigate the association between HL and trauma in daily life using National Health Insurance Service National Sample Cohort data of Korea.

Materials And Methods: People who were registered with severe or mild hearing disability by the Korean government from 2002 to 2015, were included in this study.

Intratympanic membrane cholesteatoma after traumatic tympanic membrane perforation: a case report.

Background: Intratympanic membrane cholesteatoma presents as an asymptomatic, white, round mass on the tympanic membrane, and is usually detected incidentally in children.

Case Presentation: A 12-year-old Korean boy visited our otorhinolaryngology clinic for a whitish mass on the right tympanic membrane. He had a history of traumatic tympanic membrane perforation in the right ear that had occurred 1 year prior, which had healed well with a paper patch placement.

Incidence of peripheral vestibular disorders based on population data of South Korea.

Background: There have been no comprehensive studies on the incidence of peripheral vestibular disorders based on population-based data for a long-term period.

Objective: We investigated the incidence of peripheral vestibular disorders using population-based data representing the whole population of South Korea.

Methods: This study used the National Health Insurance Service data in Korea from 2008 to 2020.

Monthly and seasonal variations in vestibular neuritis.

Seasonal variations in vestibular neuritis (VN) could support the etiology of viral infection. However, several recent studies revealed no significant seasonal variations in VN. Further studies are necessary to determine the etiology of VN.

Distribution of Medical Service Use for Facial Palsy Between Medicine and Traditional Korean Medicine Based on Population-Based Data of Korea.

We investigated the distribution of medical service uses for Bell's palsy and Ramsay Hunt syndrome between medicine and traditional Korean medicine using the National Health Insurance Service National Sample Cohort data of Korea from 2006 to 2015. Patients were identified with diagnostic codes and medication or treatment claim codes. For Bell's palsy, there were 5,970 (68.

Risk factors for Bell's palsy based on the Korean National Health Insurance Service National Sample Cohort data.

The associations between hypertension, diabetes, and dyslipidemia with Bell's palsy have been controversial and only a few studies have assessed risk factors for Bell's palsy based on population-based data. The aim of the present study was to evaluate whether sociodemographic factors such as sex, age, residence, household income, and metabolic diseases such as hypertension, diabetes, and dyslipidemia were risk factors for Bell's palsy using the National Health Insurance Service National Sample Cohort data of Korea. Patients who visited an outpatient clinic twice or more or had one or more admission and received steroid medication under the International Classification of Diseases diagnostic codes for Bell's palsy from 2006 to 2015 were defined as patients with Bell's palsy in this study.

The Association between the Concentration of Heavy Metals in the Indoor Atmosphere and Atopic Dermatitis Symptoms in Children Aged between 4 and 13 Years: A Pilot Study.

Background: A correlation between the harmful effects of air pollutants and atopic dermatitis has been reported. There are few studies on the correlation between the concentration of heavy metals in the indoor atmosphere and symptoms of atopic dermatitis.

Methods: Twenty-two homes of children showing atopic dermatitis symptoms were enrolled, and eighteen homes with similarly aged children without symptoms or a history of atopic dermatitis participated as a control group.

The Associations of Tonsillectomy with Adenoidectomy with Pneumonia and Appendicitis Based on National Sample Cohort Data from the Korean National Health Insurance Service.

 The association between tonsillectomy with adenoidectomy (T&A) with appendicitis is controversial, and the association of T&A with pneumonia has not been investigated.  To investigate the associations of T&A with pneumonia and appendicitis using data from the Korean National Health Insurance Service National Sample Cohort.  We selected patients between the ages of 3 and 10 years who had undergone T&A in 2005 and were monitored since the performance of the T&A until 2013.

Sudden sensorineural hearing loss after COVID-19 vaccination.

Coronavirus disease 2019 (COVID-19) spread rapidly and was declared a pandemic. In this situation, vaccination for COVID-19 is important and has been prompted in many countries. Rare serious adverse events including Guillain-Barré syndrome, thrombosis with thrombocytopenia syndrome, and myocarditis after COVID-19 vaccinations have been reported.

Neonatal and maternal risk factors for hearing loss in children based on population-based data of Korea.

Objectives: We identified the neonatal and maternal risk factors for hearing loss (HL) in children using National Health Insurance Service data of Korea.

Methods: We retrospectively analyzed data from the National Health Insurance Service. Infants born from 2007 to 2013 were tracked to 2015.

Incidence of Olfactory Dysfunction and Associated Factors: A Nationwide Cohort Study From South Korea.

Objectives: Olfactory dysfunction, a reduced or complete loss of the ability to smell, is gaining attention because of its substantial impact on an individual's quality of life and the possibility that it is an important sign of underlying disease. However, olfactory dysfunction is underdiagnosed in the general population due to diagnostic difficulty and unpredictable prognosis. This study aimed to evaluate the prevalence of clinically diagnosed olfactory dysfunction in South Korea by using well-organized, nationwide, population-based cohort data, and the associations between olfactory dysfunction and risk of neurodegenerative disorders.

Melanocytic Nevus in the External Auditory Canal with Keratin Accumulation.

Nevus is a benign melanocytic neoplasm and the most common type of skin tumor. It may occur anywhere on the skin, but it is rare in the external auditory canal (EAC). We present a case of melanocytic nevus in the EAC with keratin accumulation.

Schwannoma in the External Auditory Canal.

Schwannoma is a slow-growing, benign tumor originating from the Schwann cells of peripheral nerve sheaths. Schwannoma in the external auditory canal is rare but should be included in the possible diagnosis of a cystic mass. If schwannoma is suspected, computed tomography or magnetic resonance imaging should be performed to explore tumor size, location, possible extension, and origin before excision.

Monthly and seasonal variations in benign paroxysmal positional vertigo.

Background: Several studies on seasonal variation in benign paroxysmal positional vertigo (BPPV) have been reported. However, the association between season and BPPV remains controversial; thus, further study is required.

Objective: We analyzed patients with BPPV to evaluate monthly and seasonal variations.

Spongiotic osteoma in the external auditory canal: Two cases of a rare tumor.

Osteoma of the external auditory canal is a rare benign tumor with an estimated incidence of 0.05% of total otologic surgeries. In most cases, an osteoma in the external auditory canal does not cause symptoms because the tumor grows slowly and does not occlude the ear canal.

Myopericytoma in the Antitragus of the Auricle: A Rare Tumor.

A myopericytoma in the auricle is rare. If an auricle contains a large, firm, red-brown mass, excision should be considered because the mass may be a myopericytoma. After excision, histopathological and immunohistochemical diagnoses are essential to rule out malignancy.