Biomarkers.

Background: Amyloid-β is widely known as a substantial biomarker in the diagnosis of Alzheimer's disease. However, detection of amyloid-β through neuroimaging techniques requires huge amounts of resources. There is a growing demand to detect these pathologies based on digital biomarkers.

Maternal and Neonatal Outcomes Based on Changes in Glycosylated Hemoglobin Levels During First and Second Trimesters of Pregnancy in Women with Pregestational Diabetes: Multicenter, Retrospective Cohort Study in South Korea.

This study compared glycosylated hemoglobin (HbA1c) levels in the first and second trimesters of pregnancy and assessed maternal and neonatal outcomes according to HbA1c variations among women with pregestational diabetes. This retrospective, multicenter Korean study involved mothers with diabetes who had given birth in 17 hospitals. A total of 292 women were divided into three groups based on HbA1c levels during the first and second trimesters: women with HbA1c levels maintained at <6.

A Lightweight and High Yield Complementary Metal-Oxide Semiconductor True Random Number Generator with Lightweight Photon Post-Processing.

This paper introduces a novel TRNG architecture that employs a wave converter to generate random outputs from the jitter noise in a customized ring oscillator (RO). Using a current-starved inverter, the proposed RO offers the option of operating three different oscillation frequencies from a single oscillator. To assess its performance, the core TRNG proposed in this work was designed with multiple samples, employing various transistor sizes for 28 nm CMOS processes.

Comparisons of functional movements and core muscle activity in women according to Pilates proficiency.

Introduction: This study aims to investigate the differences in functional movements and core muscle activities between experienced and novice practitioners during Pilates exercises.

Methods: Thirty-eight participants were recruited for the study, comprising 19 experienced and 19 novice Pilates practitioners. Participants performed functional movement screening (FMS) tests and six Pilates exercises at the basic, intermediate, and advanced levels.

Improved biohydrogen production using Ni/ZrCeO loaded on foam reactor through steam gasification of sewage sludge.

The pervasive generation of sewage sludge (SES) and deficiencies in its disposal methods have resulted in several significant environmental and human health challenges. This study explored the catalytic effect of nickel (Ni)-based CeO, ZrO, Zr.Ce.

Coupling photocatalytic CO reduction and CHOH oxidation for selective dimethoxymethane production.

Currently, conventional dimethoxymethane synthesis methods are environmentally unfriendly. Here, we report a photo-redox catalysis system to generate dimethoxymethane using a silver and tungsten co-modified blue titanium dioxide catalyst (Ag.W-BTO) by coupling CO reduction and CHOH oxidation under mild conditions.

Medical imaging in cancer cachexia.

Cancer cachexia, often referred to as "wasting syndrome," is characterized by fatigue, weakness, and involuntary weight loss. This syndrome is concomitant with progressive skeletal muscle atrophy with or without adipose tissue loss and is frequently accompanied by systemic inflammation. Understanding the complexities of cancer cachexia is crucial for early detection and intervention, and it is also paramount for enhancing patient outcomes.

Insight into Facile Ion Diffusion in Resistive Switching Medium toward Low Operating Voltage Memory.

The rapid increase in data storage worldwide demands a substantial amount of energy consumption annually. Studies looking at low power consumption accompanied by high-performance memory are essential for next-generation memory. Here, Graphdiyne oxide (GDYO), characterized by facile resistive switching behavior, is systematically reported toward a low switching voltage memristor.

SCANPatient: study protocol for a multi-centre, batched, stepped wedge, comparative effectiveness, randomised clinical trial of synoptic reporting of computerised tomography (CT) scans assessing cancers of the pancreas.

Background: Complete surgical removal of pancreatic ductal adenocarcinoma (PDAC) is central to all curative treatment approaches for this aggressive disease, yet this is only possible in patients technically amenable to resection. Hence, an accurate assessment of whether patients are suitable for surgery is of paramount importance. The SCANPatient trial aims to test whether implementing a structured synoptic radiological report results in increased institutional accuracy in defining surgical resectability of non-metastatic PDAC.

Production of biodiesel via esterification of coffee waste-derived bio-oil using sulfonated catalysts.

Catalytic esterification of acid-rich coffee waste-derived bio-oil was performed using sulfonated metal oxide catalysts (AlO, MgO, ZrO, and TiO) and ethanol to produce fatty acid alkyl esters. The potential of the sulfonated catalysts for esterification decreased in the following order: Ti-SO > Zr-SO > Al-SO > Mg-SO. Particularly, Ti-SO and Zr-SO resulted in 91.

Post-radiotherapy stage III/IV non-small cell lung cancer radiomics research: a systematic review and comparison of CLEAR and RQS frameworks.

Background: Lung cancer, the second most common cancer, presents persistently dismal prognoses. Radiomics, a promising field, aims to provide novel imaging biomarkers to improve outcomes. However, clinical translation faces reproducibility challenges, despite efforts to address them with quality scoring tools.

Glucose tolerance test with a single abnormal value as a predictor of type 2 diabetes mellitus: a multicenter retrospective study.

Clinical implication of a single abnormal value (SAV) in the 100 g oral glucose tolerance test during pregnancy has not been established. We aimed to evaluate the risk of postpartum type 2 diabetes mellitus (T2DM) and investigate adverse pregnancy outcomes in women with SAV, using a retrospective database, from seven medical centers of Korea. Based on the Carpenter-Coustan criteria using two-step approach, pregnancy and postpartum outcomes were compared, among normoglycemic, SAV, and gestational diabetes mellitus (GDM) groups.

Risk factors for pregnancy-associated heart failure with preserved ejection fraction and adverse pregnancy outcomes: a cross-sectional study.

Background: Although pregnancy-associated heart failure with preserved ejection fraction (HFpEF) is increasing and contributing to maternal morbidity, little is known about its impact on pregnancy. We examined the risk factors for and adverse pregnancy outcomes of HFpEF in pregnant women.

Methods: We conducted a cross-sectional analysis of pregnancy-related hospitalizations from 2009 to 2020 using the perinatal database of seven multicenters.

Congenital Anomalies in Multiple Pregnancy: A Literature Review.

Importance: Multiple pregnancy is relatively common in many countries and is associated with various pregnancy complications, including preterm birth, low birth weight, and congenital anomalies. In particular, a poorer prognosis has been reported when congenital anomalies overlap with other pregnancy complications in multiple pregnancy compared with singleton pregnancy.

Objective: This study reviews the characteristics of congenital anomalies that occur in multiple gestations as compared with singleton pregnancies.

Enhancing microbial CO electrocatalysis for multicarbon reduction in a wet amine-based catholyte.

Microbial CO electroreduction (mCO2ER) offers a promising approach for producing high-value multicarbon reductants from CO by combining CO fixing microorganisms with conducting materials (i. e., cathodes).

Association between placental location and cord insertion site with pre-eclampsia: a retrospective cohort study.

Objective: The relationship between placental location in pregnancies without previa and adverse pregnancy outcomes has not been well studied. Additionally, the impact of abnormal cord insertion sites remains controversial. Therefore, the objective of this study was to explore the adverse outcomes associated with placental location and abnormal cord insertion in nulliparous women and to assess their impact on pregnancy outcomes.