Publications by authors named "Hyun Ji Boo"
Characterization of CD8 virtual memory T cells in IL-4 knockout mice using single-cell RNA sequencing.
Biochem Biophys Res Commun
December 2024
Article Synopsis
- The study investigates the development of virtual memory (VM) CD8 T cells in the absence of Interleukin-4 (IL-4) by using IL-4 knockout (KO) C57BL/6 mice to compare with wild-type (WT) mice.
- Researchers identified different CD8 T cell subtypes through single-cell RNA sequencing, highlighting significant changes in the expression of various genes and cell surface markers between the two mouse types.
- The findings indicate that in the absence of IL-4, specific VM CD8 T cells (especially those expressing Ly6a) may rely on type I interferon signaling to maintain their population in peripheral tissues.
Background: Previous studies have investigated the use of transcranial direct current stimulation (tDCS) for pain management. The studies investigating therapeutic neuromodulation with tDCS for lower extremity pain are scarce and inconclusive.
Objective: The aim of the present study was to analyze the effects of cerebellar tDCS on lower extremity sensory and pain thresholds in healthy volunteers.