Covalent immobilization of human serum albumin on cellulose acetate membrane for scavenging amyloid beta - A stepping extracorporeal strategy for ameliorating Alzheimer's disease.

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by interrupted neurocognitive functions and impaired mental development presumably caused by the accumulation of amyloid beta (Aβ) in the form of plaques. Targeting Aβ has been considered a promising approach for treating AD. In the current study, human serum albumin (HSA), a natural Aβ binder, is covalently immobilized onto the surface of a cellulose acetate (CA) membrane to devise an extracorporeal Aβ sequester.

CuBTC Metal-Organic Framework Decorated with FeBTC Nanoparticles with Enhance Water Stability for Environmental Remediation Applications.

Metal-organic frameworks (MOFs) based on Cu-benzene tricarboxylate (CuBTC) are widely used for gas storage and removal applications. However, they readily lose their crystal structures under humid conditions, limiting their practical applications. This structural decomposition reduces the specific surface area, gas adsorption capability, and recyclability of CuBTC considerably.

Development and evaluation of bioinspired pH-responsive sericin-chitosan-based hydrogel for controlled colonic delivery of PETase: Harnessing PETase-triggered degradation of microplastics.

The gravity of threats posed by microplastic pollution to the environment cannot be overestimated. Being ubiquitous in the living environment, microplastics reach humans through the food chain causing various hazardous effects. Microplastics can be effectively degraded by PETase enzymes.

ZIF-8 Membrane Separation Performance Tuning by Vapor Phase Ligand Treatment.

Vapor phase ligand treatment (VPLT) of 2-aminobenzimidazole (2abIm) for 2-methylimidazole (2mIm) in ZIF-8 membranes prepared by two different methods (LIPS: ligand induced permselectivation and RTD: rapid thermal deposition) results in a notable shift of the molecular level cut-off to smaller molecules establishing selectivity improvements from ca. 1.8 to 5 for O /N ; 2.

Alkylamine-Integrated Metal-Organic Framework-Based Waveguide Sensors for Efficient Detection of Carbon Dioxide from Humid Gas Streams.

Metal-organic framework (MOF)-based chemical sensors have recently been demonstrated to be highly selective, sensitive, and reversible for CO sensing across a range of platforms including optical fiber and surface acoustic wave-based sensors. However, interference of water molecules is a primary issue in CO sensing systems based upon MOF layers due to cross-sensitivity, stability of MOF-based materials in humid conditions, and associated baseline drift over the lifetime of sensors. Herein, we develop a simple approach of alleviating the negative effect of water vapor to the optical fiber sensor by using alkylamine (i.

High-Flux Zeolitic Imidazolate Framework Membranes for Propylene/Propane Separation by Postsynthetic Linker Exchange.

While zeolitic imidazolate framework, ZIF-8, membranes show impressive propylene/propane separation, their throughput needs to be greatly improved for practical applications. A method is described that drastically reduces the effective thickness of ZIF-8 membranes, thereby substantially improving their propylene permeance (that is, flux). The new strategy is based on a controlled single-crystal to single-crystal linker exchange of 2-methylimidazole in ZIF-8 membrane grains with 2-imidazolecarboxaldehyde (ZIF-90 linker), thereby enlarging the effective aperture size of ZIF-8.

Defect-induced ripening of zeolitic-imidazolate framework ZIF-8 and its implication to vapor-phase membrane synthesis.

We report for the first time that ZIF-8 crystals undergo an Ostwald-ripening-like process without degradation in the presence of a ligand vapor. The ripening process is dependent on the defect density of the crystals: the more defective the more amenable to the ripening. The process was adapted to synthesize ultra-thin ZIF-8 membranes by vapor-phase secondary growth.

Heteroepitaxially grown zeolitic imidazolate framework membranes with unprecedented propylene/propane separation performances.

Propylene/propane separation is one of the most challenging separations, currently achieved by energy-intensive cryogenic distillation. Despite the great potential for energy-efficient membrane-based separations, no commercial membranes are currently available due to the limitations of current polymeric materials. Zeolitic imidazolate framework, ZIF-8, with the effective aperture size of ∼4.

Synthesis and characterization of Cu3(BTC)2 membranes by thermal spray seeding and secondary growth.

Crack-free Cu3(BTC)2 membranes were successfully prepared by thermal spray seeding and secondary growth method. Thermal spray seeding method, combining thermal seeding and pressurized spraying, uniformly distributed seed solution on the support, anchoring seed crystals tightly on the support. After secondary growth of the seeded support in the autoclave, continuous crack-free membrane was obtained by controlling cooling and drying steps.

In situ synthesis of thin zeolitic-imidazolate framework ZIF-8 membranes exhibiting exceptionally high propylene/propane separation.

Metal-organic frameworks (MOFs) are a class of hybrid porous crystalline materials comprising of metal centers coordinated to organic linkers. Owing to their well-defined pores and cavities in the scale of molecules combined with abundant surface chemistry, MOFs offer unprecedented opportunities for a wide range of applications including membrane-based gas separations. It is not straightforward (often requiring multiple steps) to prepare membranes of MOFs due to the fact that the heterogeneous nucleation and growth of MOF crystals on porous supports are not generally favored.

Highly propylene-selective supported zeolite-imidazolate framework (ZIF-8) membranes synthesized by rapid microwave-assisted seeding and secondary growth.

Here we report a rapid and simple microwave-assisted seeding technique for the synthesis of high-quality ZIF-8 membranes with an average propylene-propane selectivity of about 40. The new seeding method was found to be applicable to other ZIFs including ZIF-7 and SIM-1.

Sol-gel synthesis and characterization of nanostructured TiO2/gamma-Al2O3 composite membranes.

Nanostructured TiO2/gamma-Al2O3 composite membranes with various compositions were prepared by sol-gel method. The structural and textural properties of the composite membranes could be modified by the mixing ratio of boehmite sol and titania sol, and calcination temperature. The existence of alumina in the composite membranes retarded anatase-to-rutile phase transformation, resulting in stabilization of textural properties.