A Study on the Preliminary Plan for Environmental Health in Seoul, Korea.

In the Republic of Korea, the Environmental Health Act was amended in January 2021, making it mandatory for each local government to establish a plan for environmental health. Accordingly, the Seoul Metropolitan Government (SMG) must establish the Local Plan for Environmental Health (LPEH) to protect citizens' health from environmental hazards. The plan would support existing environmental health policies in Seoul to improve population health and achieve their goals.

Asymmetric Divergent Total Syntheses of (+)-Decursivine and (+)- Serotobenine via Intramolecular Fischer Indole Synthesis.

A new asymmetric synthetic route to (+)-decursivine and (+)-serotobenine is formulated. The key developments are the de novo construction of the crucial eight-membered 3,4-fused tricyclic indole ring engaged by the intramolecular Fischer indole synthesis and the stereocontrolled assembly of the dihydrobenzofuran subunit mediated by the asymmetric intramolecular Rh-carbenoid C-H insertion. BF-mediated selective C15 epimerization followed by removal of the amine masking groups completed the target natural compounds' asymmetric and divergent total syntheses.

Effect of air pollutant emission reduction policies on hospital visits for asthma in Seoul, Korea; Quasi-experimental study.

To improve air quality and reduce adverse health effects due to air pollutants, Seoul metropolitan government has introduced emission reduction policies in Seoul metropolitan area since 2007. As a result, air quality in Seoul has improved. However, no study has reported whether emission reduction policies have affected respiratory morbidities in Korea.

Spatial variation in lag structure in the short-term effects of air pollution on mortality in seven major South Korean cities, 2006-2013.

Lag is one of the major uncertainties in the heterogeneity of short-term effects of particulate matter with aerodynamic diameter <10 μm (PM) on mortality. This study aimed to explore spatial variations in extended lag effects of PM on all-cause mortality, cardiovascular mortality and respiratory mortality in seven major South Korean cities over a period spanning 2006-2013. We did time-series analysis using generalized linear models and adjusted for temporal trend, day of the week, holiday, influenza epidemic, and weather.

Association between Urban Greenness and Depressive Symptoms: Evaluation of Greenness Using Various Indicators.

An increasing number of studies have suggested benefits of greenness exposure on mental health. We examined the association between urban greenness and depressive symptoms in adults in the general population living in the seven major cities in Korea ( = 65,128). Using data from the Korean Community Health Survey 2009, depressive symptoms were measured on the Center for Epidemiological Studies Depression Scale (CES-D).

Difference in temporal variation of temperature-related mortality risk in seven major South Korean cities spanning 1998-2013.

Temporal variation of temperature-related mortality risk is an important issue in climate change era. However, difference in this temporal variation across cities in South Korea remains unclear. The aim of this study was to explore whether temporal variation might differ spatially across seven metropolitan cities of Korea during the period of 1998-2013.

Assessing the cold temperature effect on hospital visit by allergic rhinitis in Seoul, Korea.

The association between temperature and health outcome has been studied in worldwide. However, studies for mild diseases such as AR, with high prevalence and considerable economic burden, are lacking compared to other relatively severe respiratory diseases. We aimed to assess the trend of hospital visit by AR and estimate the cold temperature effect on hospital visit by allergic rhinitis in Seoul, Korea, 2003-2011.

Assessment of temporal variation for the risk of particulate matters on asthma hospitalization.

Increased ambient concentration of particulate matters are considered as one of major causes for increased prevalence or exacerbation of asthma or asthma like symptoms. Recently, possible temporal variation in risks of PM on mortality has been suggested. We investigated short-term effect of both PM and PM on asthma hospitalization, and assessed temporal variation of PM risks in Seoul, Korea, 2003-2011.

Effect of solar irradiation on serum specific immunoglobulin E to house-dust mite.

Background: The relationship between sensitization to Dermatophagoides species and solar irradiation, as reflected by vitamin D, remains elusive.

Objective: We investigated the lag time and the cumulative and maximum effects of exposure to solar irradiation on sensitization to house-dust mites.

Methods: A time series study design was applied to solar irradiation (MJ/m(2)) and relative humidity (%) for specific immunoglobulin E (IgE) levels against Dermatophagoides pteronyssinus (n = 20,451) and Dermatophagoides farinae (n = 22,824).

Effects of ambient air particles on mortality in Seoul: Have the effects changed over time?

Background: Several studies have shown that there may be temporal variation in PM short-term effect on mortality. This temporal pattern may play an important role in evaluating air quality policies.

Objectives: We investigated temporal variation in the association between PM and mortality in Seoul, Korea, 1998-2011.

Has the impact of temperature on mortality really decreased over time?

Many studies have reported that the temperature effect on mortality has decreased over time. However, most of those studies did not consider lag times longer than 10 days, which is frequently used to explore its effect net out compensatory effect (harvesting) and lag effects. We sought to examine the temporal variation of the temperature effect on mortality, considering both a lag effect and mortality displacement.

Plasma calcium and risk of hypertension: propensity score analysis using data from the korean genome and epidemiology study.

Objective: To investigate associations between plasma calcium and future incidence of hypertension in a healthy population.

Methods: We used prospective data from Ansung and Ansan cohorts (n = 10,038) of the Korean Genome and Epidemiology Study. Data from baseline (2001-02) to the fourth study (2007-08) were used.