Publications by authors named "Hyojeong Lee"

The auditory brainstem response (ABR) is a noninvasive test that measures neural activity in response to auditory stimuli. Racial differences in head shape have provided strong evidence for specific normative data and accurate device calibration. International standards emphasize the need for standardized procedures and references.

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The emergence of rice black-streaked dwarf virus (RBSDV) poses a significant threat to global cereal crop cultivation, necessitating the urgent development of reliable detection and quantification techniques. This study introduces a reliable approach for the precise and sensitive quantification of the RBSDV in cereal crop samples, employing a reverse transcription digital polymerase chain reaction (RT-dPCR) assay. We assessed the specificity and sensitivity of the RT-dPCR assay proposed for precise RBSDV detection and quantification.

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The possibility of new viruses emerging in various regions worldwide has increased due to a combination of factors, including climate change and the expansion of international trading. Plant viruses spread through various transmission routes, encompassing well-known avenues such as pollen, seeds, and insects. However, research on potential transmission routes beyond these known mechanisms has remained limited.

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Objective: Recent studies have shown that transcutaneous vagal nerve stimulation (tVNS) holds promise as a treatment for neurological or psychiatric disease through the ability to modulate neural activity in some brain regions without an invasive procedure. The objective of this study was to identify the neural correlates underlying the effects of tVNS.

Methods: Twenty right-handed healthy subjects with normal hearing participated in this study.

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Pure-tone audiometry, using an audiometer, is the fundamental hearing test for diagnosing hearing loss. The requirements of the devices and the detailed process for calibrating the related equipment are described in international standards. However, traceable calibration and uncertainty evaluation processes are not widely accepted or applied to the qualification and maintenance of audiometric equipment.

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Recent studies have reported chronic rhinosinusitis (CRS) as an independent risk factor for stroke. However, the association with stroke depending on the affected sinuses has not been explored. This study aimed to elucidate the side- and sinus-specific relationship between CRS and ischemic stroke through imaging analyses.

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SARS-CoV-2 has become a global public health problem. Acute respiratory distress syndrome (ARDS) is the leading cause of death due to the SARS-CoV-2 infection. Pulmonary fibrosis (PF) is a severe and frequently reported COVID-19 sequela.

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A special differential interferometer consisting of two gratings was developed for diagnostics of plasma density. Compared with other differential interferometers, our system has an important advantage that the shear distance, shear direction, and fringe width can be adjusted , enabling easy control of the parameters. This feature allows precise tuning of the two probe beams in the interferometer for rigorous differential phase diagnosis and more accurate information of the plasma density can be obtained.

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orchids are one of the most popular ornamental plants. More than thirty orchid viruses have been reported, and virus-infected orchids significantly lose their commercial value. Therefore, the development of improved viral disease detection methods could be useful for quality control in orchid cultivation.

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Background: Eye movement tests remain significantly underutilized in emergency departments and primary healthcare units, despite their superior diagnostic sensitivity compared to neuroimaging modalities for the differential diagnosis of acute vertigo. This underutilization may be attributed to a potential lack of awareness regarding these tests and the absence of appropriate tools for detecting nystagmus. This study aimed to develop a nystagmus measurement algorithm using a lightweight deep-learning model that recognizes the ocular regions.

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Adolescent idiopathic scoliosis is a commonly encountered condition often diagnosed on screening examination. Underlying, asymptomatic neural axis abnormalities may be present at the time of diagnosis. At certain institutions, total spine MRI is obtained preoperatively to identify these abnormalities.

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Article Synopsis
  • This study examines hearing thresholds to understand changes in the human auditory system across different ages, using both the ISO 7029 standard and new data from four countries.
  • The research compares average hearing threshold levels under similar conditions, focusing on frequency ranges from 125 Hz to 12,500 Hz.
  • Findings indicate that while most hearing threshold data align with ISO 7029, some deviations exist based on age and sex, highlighting the need for integrating international data in potential ISO 7029 revisions.
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Adolescent idiopathic scoliosis is a commonly encountered condition often diagnosed on screening examination. Underlying, asymptomatic neural axis abnormalities may be present at the time of diagnosis. At certain institutions, total spine MRI is obtained preoperatively to identify these abnormalities.

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Article Synopsis
  • The study focuses on synthesizing poly(propylene carbonate) (PPC) polyols, an eco-friendly material made from CO, with varying carbonate levels to enhance their use in making polyurethane products.* -
  • Heterogeneous Zn/Co double metal cyanide catalysts, using poly(ethylene glycol)--poly(propylene glycol)--poly(ethylene glycol) (P123) as a complexing agent, were used to optimize the synthesis process, especially at a calcination temperature of 100 °C for improved catalytic performance.* -
  • The results indicated that the optimized PPC polyols had up to 32.8 wt % propylene carbonate, which increased intermolecular attraction and positively affected the rheological properties, making them a
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Article Synopsis
  • This study examines the importance of using international standards like ISO and IEC for conducting hearing tests, emphasizing their role in uniform design, calibration, and assessment of testing instruments and methods.
  • By following these standards, hearing tests can achieve greater accuracy, reliability, and consistency, fostering global data sharing and research collaboration.
  • However, challenges like equipment variability, slow updates to standards, and cultural differences can hinder the effectiveness of these protocols, suggesting a need for local adaptation to enhance their relevance while still aligning with global frameworks.
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Plants are challenged by various pathogens throughout their lives, such as bacteria, viruses, fungi, and insects; consequently, they have evolved several defense mechanisms. In addition, plants have developed localized and systematic immune responses due to biotic and abiotic stress exposure. Animals are known to activate DNA damage responses (DDRs) and DNA damage sensor immune signals in response to stress, and the process is well studied in animal systems.

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Article Synopsis
  • The antioxidative proteolytic fraction, MA-1, was purified and shown to have significantly increased specific activity (89-fold) while retaining 42.5% of its activity during purifying processes.
  • MA-1 demonstrated stability in the presence of various metal ions and solvents, while exhibiting a chymotrypsin-like specificity for certain substrates and optimal activity at a temperature of 40 °C and pH of 5.5.
  • This enzyme also showed strong fibrinolytic activity, capable of hydrolyzing fibrinogen chains, and displayed an antithrombotic effect in animal studies without causing hemorrhagic complications, suggesting its potential in cardiovascular disease prevention.
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Acne vulgaris is a common skin disease characterized by increased sebum production, inflammation, and (CA: formerly ) hyperproliferation in pilosebaceous follicles. This study evaluated the efficacy of FRO, a formula composed of fermented Stokes and , against acne pathogenesis via antimicrobial assessment and an in vitro analysis. Stimulated model cells treated with hormones, CA, or lipopolysaccharide (LPS) were designed based on the characteristics of acne pathogenesis, including inflammation and sebum hypersecretion.

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Wheat ( L.) is one of the most important staple crops in the world, along with maize and rice. More than 50 plant viruses are known to infect wheat worldwide.

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Article Synopsis
  • Global climate change and international trade are increasing the risk of introducing new plant viruses across borders, as seen in the case of Ixora coccinea showing virus-like symptoms.
  • The Oxford Nanopore Technologies MinION platform was used to identify jasmine virus H (JaVH), revealing a complete genome sequence that closely resembles a variant found in Jasminum sambac from China.
  • This study marks the first reported natural infection of Ixora coccinea by JaVH and highlights the effectiveness of rapid nanopore sequencing for accurate plant virus detection and surveillance.
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Objectives: To train participants to localize sound using virtual reality (VR) technology, appropriate auditory stimuli that contain accurate spatial cues are essential. The generic head-related transfer function that grounds the programmed spatial audio in VR does not reflect individual variation in monaural spatial cues, which is critical for auditory spatial perception in patients with single-sided deafness (SSD). As binaural difference cues are unavailable, auditory spatial perception is a typical problem in the SSD population and warrants intervention.

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