Fucoidan isolated from fermented Sargassum fusiforme suppresses oxidative stress through stimulating the expression of superoxidase dismutase and catalase by regulating Nrf2 signaling pathway.

In this study, a fucoidan (SFF-PS-F5) with a molecular weight of 213.33 kDa was isolated from fermented Sargassum fusiforme and the antioxidant activity of SFF-PS-F5 was investigated in vitro in Vero cells and in vivo in zebrafish. SFF-PS-F5 contains 91.