Publications by authors named "Hyo-Eun Kang"
Article Synopsis
- Microfluidic paper-based analytical devices (μPADs) are praised for being affordable and portable tools for point-of-care testing, but traditional fabrication methods can be complex and costly, particularly in low-resource environments.
- This research presents a new fabrication method for μPADs using 3D-printed chambers and super glue vapor, allowing for quick and easy production, effective in just 5 minutes without specialized training.
- The study's significance lies in its introduction of a simplified way to create μPADs for detecting various analytes, including glucose and heavy metals, potentially broadening their use in diagnostics.
Article Synopsis
- BRCA1 and BRCA2 are crucial genes for DNA repair, and testing for mutations can help in understanding specific cancer traits and treatment options, but it's often complex.
- In a study involving 321 patients, genetic testing identified 26 with harmful BRCA variants and noted common mutations in genes like TP53 and PIK3CA across samples.
- The analysis showed significant differences in tumor mutation burden between patients with wild-type BRCA genes and those with pathogenic variants, highlighting the value of using next-generation sequencing for cancer diagnostics.
Sperm motility is a crucial factor for normal fertilisation that is partly supported by mitochondrial activity. Enzymatic biofuel cells (EBFCs) generate electric currents by an electron grade from anodic to cathodic electrodes in a culture media. We demonstrate that electrical stimulation by EBFC at the nano-Ampere range enhances sperm motility that can potentially allow the development of a new therapeutic tool for male infertility, including poor motility.
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