Publications by authors named "Hyo Sik Jo"
Article Synopsis
- Docosahexaenoic acid (DHA), an omega-3 fatty acid found in fish oil, has anti-inflammatory and disease-inhibiting properties, particularly in breast cancer and its progression through the epithelial-to-mesenchymal transition (EMT) process.
- Gremlin-1 (GREM1) promotes EMT by upregulating markers such as N-cadherin, vimentin, and Slug, facilitating breast cancer cell migration and influencing ERK signaling pathways.
- DHA counteracts GREM1's effects by reducing GREM1 expression and blocking mesenchymal gene expression and cell migration, suggesting it could be a promising therapeutic agent against EMT in breast cancer.
