Publications by authors named "Hyo Jae Shin"
Article Synopsis
- * The study analyzed public RNA sequencing datasets, revealing that elevated COL4A1 expression correlates with lower survival rates in patients with glioma, pancreatic adenocarcinoma, melanoma, and stomach cancer, indicating its potential as a poor prognosis biomarker.
- * Notably, COL4A1 is primarily expressed in cancer-associated stromal cells, like fibroblasts and endothelial cells, and its levels are closely associated with pro-tumoral immune cell signatures and immunosuppressive factors, suggesting a role in shaping the
Cereblon (CRBN) is a component of the E3 ubiquitin ligase complex that plays crucial roles in various cellular processes. However, no systematic studies on the expression and functions of in solid tumors have been conducted to date. Here, we analyzed expression and its clinical value using several bioinformatic databases.
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