Publications by authors named "Hyerin Sohn"

We report a nanoscale morphology-regulation strategy of self-assembled double-hydrophilic block copolymers with square planar Pt compounds. The selective coordination of Pt on the chelating blocks of poly(acrylic acid)--poly(ethylene glycol) (PAA--PEG) induced the self-association of metal-chelated unimers by the known cohesive force of Pt. The block-length variation of PAA with constant PEG led to the shape transition from normal core/shell and crew-cut spheres to anisotropic pearl-string structures.

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Article Synopsis
  • The study focuses on creating hybrid nanoparticles using cationic metal-mediated self-assembly of double-hydrophilic block copolymers (DHBCs), with a special emphasis on manganese (Mn) ions due to their useful properties.
  • A new method is introduced for incorporating Mn ions into polymer assemblies by using pyrene-end-modified DHBCs, which allows for effective monitoring of these ions through fluorescence changes.
  • The resulting manganese-loaded nanoparticles (Mn-PNPs) are designed to improve water permeability and enhance magnetic resonance imaging contrast, while also analyzing how Mn's coordination compares to that of cisplatin for better understanding of metal-chelated nanoparticles.
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