Screening and Characterization of Sialic Acid-Binding Variable Lymphocyte Receptors from Hagfish.

Sialic acid is a diverse group of monosaccharides often found on the termini of - and -linked glycans as well as being components of glycoconjugates. Hypersialylation has been associated with the progression of chronic inflammation-mediated diseases such as cardiovascular disease and cancer. Given its role in infection and disease-related processes, sialic acid is a promising target for therapeutic approaches that utilize carbohydrate-binding molecules.

Spatiotemporal distribution and source analysis of PM and its chemical components in national industrial complexes of Korea: a case study of Ansan and Siheung.

This study investigated the sources and distribution characteristics of PM and its chemical components (ions, carbons, elements) at five locations within the Banwal and Sihwa National Industrial Complexes in Ansan and Siheung. These large-scale industrial clusters, comprising 7642 businesses across sectors such as petrochemicals, steel, machinery, and electronics, operate throughout the year. From 2020 to 2023, the average PM concentration in the study area was 28.

Psychiatry curriculum: How does it affect medical students' attitude toward psychiatry?

The purpose of this study was to identify the attitude of South Korean medical school students towards psychiatry and to analyze how lectures and clinical clerkship in psychiatry effect changes in students' attitudes. A total of 100 medical school students were recruited as subjects in the study, 86 of whom completed psychiatry lectures and underwent psychiatry clerkship from March 2015 to August 2018. The participating students completed a survey, which included demographic data, specialty choice, and attitude towards psychiatry.

15-Deoxy-Δ-prostaglandin J up-regulates the expression of 15-hydroxyprostaglandin dehydrogenase through DNA methyltransferase 1 inactivation.

15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is the key enzyme that catalyses the conversion of prostaglandin E to a keto metabolite. The expression of 15-PGDH is ubiquitously repressed in various human malignancies. However, the molecular mechanisms underlying down-regulation of 15-PGDH expression remain largely unknown.

Simultaneous imaging of two different cancer biomarkers using aptamer-conjugated quantum dots.

Studying gene expression profile in a single cancer cell is important because multiple genes are associated with cancer development. Quantum dots (QDs) have been utilized as biological probes for imaging and detection. QDs display specific optical and electrical properties that depend on their size that can be applied for imaging and sensing applications.