Synopsis of recent research by authors named "Hyeok Gu Kang"
- Hyeok Gu Kang's research primarily focuses on understanding the molecular mechanisms involved in various aggressive cancers, including triple-negative breast cancer (TNBC), gastric cancer, and glioblastoma, with an emphasis on the roles of microRNAs and protein interactions in tumor progression.
- Significant findings include the identification of miR-371b-5p and miR-320c as critical regulators in TNBC, where their expression levels influence tumor growth and response to chemotherapy, highlighting potential therapeutic targets.
- Kang's work also reveals interactions between signaling pathways (e.g., WNT and STAT3) and epigenetic modifiers (e.g., KDM4C), suggesting that targeting these pathways may provide new strategies for cancer treatment while avoiding adverse effects associated with direct pathway inhibition.
