Publications by authors named "Hye Mi Gweon"
Article Synopsis
- - The study aims to create and validate nomograms that incorporate shear-wave elastography (SWE) data with clinical features to predict the Oncotype DX recurrence score (RS) for breast cancer patients undergoing systemic therapy.
- - Researchers analyzed data from 381 women with breast cancer, using a portion of the patients for developing the nomograms and the rest for independent validation; results showed that SWE indices are significantly related to the predicted RS values.
- - The nomograms demonstrated effective predictive capabilities, with area under the receiver operating characteristic curve (AUROC) values indicating strong performance for both lower (≥16) and higher (≥26) RS thresholds, suggesting they can assist in therapy decision-making.
This study aimed to investigate whether preoperative ultrasonographic (US) features of metastatic lymph nodes (LNs) are associated with tumor recurrence in patients with N1b papillary thyroid carcinoma (PTC). We enrolled 692 patients (mean age, 41.9 years; range, 6-80 years) who underwent total thyroidectomy and lateral compartment LN dissection between January 2009 and December 2015 and were followed-up for 12 months or longer.
View Article and Find Full Text PDFThis study aimed to assess the diagnostic performance of deep convolutional neural networks (DCNNs) in classifying breast microcalcification in screening mammograms. To this end, 1579 mammographic images were collected retrospectively from patients exhibiting suspicious microcalcification in screening mammograms between July 2007 and December 2019. Five pre-trained DCNN models and an ensemble model were used to classify the microcalcifications as either malignant or benign.
View Article and Find Full Text PDFArticle Synopsis
- A study investigated the effectiveness of abbreviated breast MRI for patients with suspicious microcalcifications detected on screening mammograms, including 80 patients undergoing the procedure before biopsy from August 2017 to September 2020.
- Results showed that abbreviated MRI significantly improved the positive predictive value (PPV) from 33.8% to 75.8%, indicating better accuracy in identifying true cases of malignancy.
- The use of abbreviated MRI also led to an 85% reduction in unnecessary biopsies for benign lesions, confirming its additional diagnostic value without missing invasive cancers.
Article Synopsis
- Objective: The study aimed to evaluate the effectiveness of texture analysis in MRI for predicting breast cancer recurrence in patients receiving neoadjuvant chemotherapy.
- Methods: It analyzed data from 130 women who underwent surgery after chemotherapy, using a random forest model and comparing the predictive accuracy of texture analysis with traditional MRI features.
- Results: This analysis found that texture assessment from MRI provided better predictive accuracy (AUC of 0.94) for recurrence compared to standard MRI features (AUC of 0.83), suggesting that it could be an important tool for prognosis in breast cancer treatment.
Article Synopsis
- The study compares mammographic density assessment using automated volumetric measurements recalibrated to the BI-RADS 5th edition against traditional visual assessments by radiologists.
- Analysis involved 4,000 mammograms, revealing that volumetric measurements indicated higher dense categories and a lower proportion of fatty tissue in patients with breast cancer compared to those without.
- The findings indicate that while the recalibrated volumetric measurements differ from visual assessments, they still show some correlation, suggesting that the recalibration has not fully aligned with visual judgment.
Article Synopsis
- A new scoring system was developed to evaluate the risk of breast cancer in patients with microcalcifications using the 5th edition of the Breast Imaging Reporting and Data System (BI-RADS).
- The study reviewed 194 lesions, found that 36% were malignant after surgery, and established significant differences in positive predictive values (PPV) for different BI-RADS categories.
- The scoring system demonstrated good accuracy with an AUROC of 0.874, helping to effectively stratify malignancy risk, and was further validated with another dataset showing similar results.
Article Synopsis
- - The study aimed to evaluate if ultrasound and MRI can predict the response of axillary lymph nodes in breast cancer patients undergoing neoadjuvant chemotherapy (NAC).
- - Researchers analyzed imaging data from 131 patients with positive axillary lymph nodes, finding significant correlations between imaging features, tumor size, and lymph node status post-surgery.
- - The results indicated that monitoring both lymph node morphology and tumor size using ultrasound and MRI is effective in predicting axillary response to NAC, with ultrasound showing the best diagnostic performance.
Background Previous studies have suggested that texture analysis is a promising tool in the diagnosis, characterization, and assessment of treatment response in various cancer types. Therefore, application of texture analysis may be helpful for early prediction of pathologic response in breast cancer. Purpose To investigate whether texture analysis of features from MRI is associated with pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer.
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- - Glycogen-rich clear cell carcinoma (GRCC) is a rare and aggressive breast cancer that hasn't been extensively studied in terms of imaging characteristics.
- - In this report, imaging findings from three GRCC cases were analyzed, revealing that mammography typically shows irregular or oval-shaped masses, while ultrasound presents a mix of cystic and solid areas.
- - On MRI, GRCC appears as a high signal intensity mass on T-weighted images, with enhancement around the edges after contrast, which may help differentiate it from other breast tumors.
Objective: To determine which preoperative breast magnetic resonance imaging (MRI) findings and clinicopathologic features are associated with positive resection margins at the time of breast-conserving surgery (BCS) in patients with breast cancer.
Materials And Methods: We reviewed preoperative breast MRI and clinicopathologic features of 120 patients (mean age, 53.3 years; age range, 27-79 years) with breast cancer who had undergone BCS in 2015.
Purpose: To evaluate the diagnostic performances of ultrasonographic (US) findings, computed tomography (CT) findings and fine needle aspiration cytology (FNAC) for the prediction of cervical lymph node (LN) metastases of papillary thyroid carcinoma (PTC) to determine which LN should be dissected.
Methods: 376 LNs in 302 patients who underwent both US-guided skin surface LN markings and CT before LN dissection were analyzed retrospectively. Indications for LN dissection were suspicious US findings of LN metastases (n = 300), suspicious CT findings (n = 67) or surgeon's request (n = 9).
Background Various size and shape of region of interest (ROI) can be applied for shear-wave elastography (SWE). Purpose To investigate the diagnostic performance of SWE according to ROI settings for breast masses. Material and Methods To measure elasticity for 142 lesions, ROIs were set as follows: circular ROIs 1 mm (ROI-1), 2 mm (ROI-2), and 3 mm (ROI-3) in diameter placed over the stiffest part of the mass; freehand ROIs drawn by tracing the border of mass (ROI-M) and the area of peritumoral increased stiffness (ROI-MR); and circular ROIs placed within the mass (ROI-C) and to encompass the area of peritumoral increased stiffness (ROI-CR).
View Article and Find Full Text PDFObjective: The purpose of this study was to compare visual assessments of mammographic breast density by radiologists using BI-RADS 4th and 5th editions in correlation with automated volumetric breast density measurements.
Materials And Methods: A total of 337 consecutive full-field digital mammographic examinations with standard views were retrospectively assessed by two radiologists for mammographic breast density according to BI-RADS 4th and 5th editions. Fully automated measurement of the volume of fibroglandular tissue and total breast and percentage breast density was performed with a commercially available software program.
Purpose: To investigate the significance of accompanying NME in invasive ductal carcinoma (IDC) on preoperative MR imaging and assess the factors affecting the significance.
Methods: Between January 2015 and February 2016, 163 consecutive patients with IDC who underwent preoperative MR imaging and subsequent surgery were enrolled and reviewed. Index cancer mass size and total extent with accompanying NME on MR images was measured and compared with pathologic size.
Shear-wave elastography in breast ultrasonography: the state of the art.
Ultrasonography
October 2017
Shear-wave elastography (SWE) is a recently developed ultrasound technique that can visualize and measure tissue elasticity. In breast ultrasonography, SWE has been shown to be useful for differentiating benign breast lesions from malignant breast lesions, and it has been suggested that SWE enhances the diagnostic performance of ultrasonography, potentially improving the specificity of conventional ultrasonography using the Breast Imaging Reporting and Data System criteria. More recently, not only has SWE been proven useful for the diagnosis of breast cancer, but has also been shown to provide valuable information that can be used as a preoperative predictor of the prognosis or response to chemotherapy.
View Article and Find Full Text PDFThe aim of this study was to evaluate shear wave elastography (SWE) for pre-operative evaluation of axillary lymph node (LN) status in patients with suspected breast cancer. A total of 130 axillary LNs in 130 patients who underwent SWE before fine-needle aspiration, core biopsy or surgery were analyzed. On gray-scale images, long and short axes, shape (elliptical or round), border (sharp or unsharp) and cortical thickening (concentric, eccentric or no fatty hilum) of LNs were assessed.
View Article and Find Full Text PDFPurpose: To compare the diagnostic performances of tomosynthesis and ultrasonography as adjunctives to digital mammography in women with dense breasts.
Methods: A total of 778 women with dense breasts underwent digital mammography with tomosynthesis and ultrasonography for screening and diagnostic purposes. The findings of tomosynthesis and ultrasonography were evaluated independently.
Objective: To retrospectively evaluate characteristics of and determine appropriate follow-up recommendations for BI-RADS category 3 lesions detected in preoperative MRI of breast cancer patients.
Methods: BI-RADS category 3 assessments were identified from the breast MRI database for 5,110 consecutive breast cancer patients who had undergone preoperative MRI and surgery. Patient and lesion characteristics, malignancy rate, and interval between lesion detection and cancer diagnosis were analysed.
Purpose: This study was designed to assess the outcomes of subcentimeter thyroid nodules with highly suspicious ultrasonography (US) features and to investigate the predictive factors associated with malignancy and aggressive biological behavior to determine appropriate candidate factors for active surveillance.
Methods: Between June 2011 and December 2013, 1866 subcentimeter thyroid nodules with highly suspicious US features that were subjected to US-guided fine needle aspiration and subsequent surgery or US follow-up of at least 2 years were evaluated. A multivariate logistic regression analysis was performed to identify independent clinical characteristics and US features associated with the malignancy rate and aggressive biological behavior.
Purpose: To correlate ultrasonographic (US) features of medullary thyroid carcinoma (MTC) with pre operative and postoperative calcitonin levels.
Materials And Methods: A total of 130 thyroid nodules diagnosed as MTC were evaluated. Two radiologists retrospectively evaluated preoperative US features according to size, shape, margin, echogenicity, type of calcification, and lymph node status.
Purpose: The goal of this study was to assess the clinicopathologic and ultrasonographic features of thyroid nodules with nondiagnostic results on repeat ultrasonography (US)-guided fineneedle aspiration biopsy (FNAB) according to size and the number of suspicious findings and to determine the proper management of nodules with consecutive nondiagnostic results.
Methods: This retrospective study included 297 nodules with nondiagnostic results on repeat FNAB that were evaluated by US over the course of at least 12 months of follow-up, a follow-up biopsy, or an operation. We compared clinical and US variables between benign and malignant nodules in thyroid nodules with repeat nondiagnostic results.
Background: The purpose of this study was to investigate the role of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) as a prognostic marker in conventional papillary thyroid carcinoma (PTC).
Methods: A total of 397 patients who underwent ultrasound-guided fine-needle aspiration biopsy (FNAB) and surgery for conventional PTCs were enrolled. The association between the Bethesda category and histopathologic result was evaluated.
Objective: The purpose of this study is to evaluate automated volumetric measurements in comparison with visual assessment of mammographic breast density by use of the fifth edition of BI-RADS.
Materials And Methods: A total of 1185 full-field digital mammography examinations with standard views were retrospectively analyzed. All images were visually assessed by two blinded radiologists according to breast density category in the fifth edition of the BI-RADS lexicon.