Publications by authors named "Hyder Mirghani"

Objectives: Dyslipidemias are major risk factors for cardiovascular disease, and other comorbidities. The focus on food and nutrition to prevent and treat cardiovascular risk factors including dyslipidemia is a paradigm shift. This is the first meta-analysis to assess the association of dates fruit and dyslipidemia in Type-2 diabetes.

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Patients admitted with prediabetes and atrial fibrillation are at high risk for major adverse cardiac or cerebrovascular events independent of confounding variables. The shared pathophysiology between these three serious but common diseases and their association with atherosclerotic cardiovascular risk factors establish a vicious circle culminating in high atherogenicity. Because of that, it is of paramount importance to perform risk stratification of patients with prediabetes to define phenotypes that benefit from various interventions.

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Background: Vitamin D deficiency is associated with severe COVID 19 and poor outcomes. However, the role of Vitamin D supplementation on mortality is controversial. The current meta analysis aimed to investigate the same among patients with COVID 19.

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Article Synopsis
  • The study compares two remote scarless thyroid surgery approaches: the transoral vestibular approach and the transareolar approach, focusing on cosmetic outcomes and postoperative pain in patients with papillary microcarcinoma.
  • A thorough meta-analysis was conducted by reviewing multiple medical databases, yielding 10 relevant studies from an initial pool of 389, leading to significant findings about the procedures.
  • Results indicate that the transoral approach provides better cosmetic results without significant differences in pain levels or outcomes related to central lymph node dissection, emphasizing the need for more extensive research.
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Type 1 diabetes is increasing and the majority of patients have poor glycemic control. Although advanced technology and nanoparticle use have greatly enhanced insulin delivery and glucose monitoring, weight gain and hypoglycemia remain major challenges and a constant source of concern for patients with type 1 diabetes. Type 1 diabetes shares some pathophysiology with type 2 diabetes, and an overlap has been reported.

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This systematic review synthesizes current evidence to evaluate the safety and efficacy of inclisiran for lowering low-density lipoprotein cholesterol (LDL-C). A thorough search was conducted across four main databases - PubMed, Web of Science, SCOPUS, and Science Direct - for relevant studies published in the literature within the last five years (2020-2024). We included seven studies with a total of 6831 participants, of which 4661 (68.

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Background: Diabetes mellitus is a chronic disease that significantly influences the patient's quality of life. This serious disease is approaching an epidemic, and the Arab countries are in the diabetes super region. Improving the patient's quality of life is vital for good glycemic control.

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Article Synopsis
  • * The review found that anemia, particularly iron deficiency anemia, is prevalent in HF patients, with a prevalence rate ranging from 33.3% to 69.8%, and is associated with higher mortality risks.
  • * Anemia appears to indicate disease severity rather than directly predicting death, showing correlations with other health issues like chronic kidney disease and heart-related complications. Future research may enhance clinical understanding and management of HF in anemic patients.
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Introduction: Remote-access scarless thyroidectomies are relatively new surgical procedures, and their uptake for cosmetic concerns is rapidly evolving. However, demographic factors, previous thyroid surgery, and culture substantially influence the patient's choice. This is the first study to assess the extensive counseling effect on the patient's preference for remote-access thyroidectomies compared to conventional transcervical approaches.

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Poor fruit and vegetable consumption is one of the 10 major risk factors for mortality. There is a misconception regarding the consumption of dates among patients with diabetes. This manuscript assessed the effects of date consumption on fasting and postprandial blood glucose, glycated hemoglobin, total cholesterol, triglycerides, low-density lipoproteins, high-density lipoproteins, and microbial markers.

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Transoral endoscopic thyroidectomy via the vestibular approach (TOETVA) represents a minimally invasive alternative to traditional open thyroidectomy (OT). The objective of this systematic review and meta-analysis was to comprehensively analyze and compare postoperative pain outcomes between conventional open thyroidectomy (COT) and TOETVA. We conducted a systematic search across multiple databases, including PubMed, Medline, Elton B.

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The global adoption of remote thyroidectomy is increasing, with the transoral endoscopic thyroidectomy vestibular approach (TOETVA) and transareolar approach (TAA) emerging as predominant methods. However, existing meta-analyses comparing these approaches to operative surgeries and short-term postoperative complications have significant limitations. To address this gap, our meta-analysis provides a comprehensive comparison between the TOETVA and TAA, focusing on operation time, intraoperative blood loss, postoperative drainage, and hospital stay duration.

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Background Thyroid disorders are caused either by excessive or inadequate thyroid hormone production or by the enlargement of the thyroid gland. Various types of thyroid disorders exist, including primary (related directly to the gland itself), secondary (related to thyroid function), and other types. This study aimed to assess the knowledge of thyroid disease manifestation and its risk factors among individuals living in Tabuk, Saudi Arabia.

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Thyroidectomy is common and is performed for malignancy, goiters with pressure symptoms, and certain types of Grave's disease. Weight and body mass index (BMI) following thyroidectomy were discussed controversially. This meta-analysis aimed to assess weight and BMI following thyroidectomy.

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Article Synopsis
  • Carpal Tunnel Syndrome (CTS) is a condition caused by the compression of the median nerve in the wrist, leading to decreased quality of life and work productivity.
  • A study in Tabuk City, Saudi Arabia found a 3.4% prevalence of CTS, with chronic diseases being a significant risk factor for its development.
  • Participants generally had good knowledge about CTS, with females and younger individuals showing higher awareness of its causes, symptoms, and treatments.
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Background: Antibiotic resistance is a global public health concern, and understanding the knowledge, attitudes, and practices (KAP) of the general population is essential for effective prevention and management. This cross-sectional study aimed to assess the KAP of antibiotic resistance among adults in Saudi Arabia.

Materials And Methods: Between August 2023 and October 2023, 1000 participants aged 16-65 years from various regions in Saudi Arabia were surveyed using an online questionnaire.

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Although psoriasis is a multi-organ disease, it is usually managed as a skin disease, ignoring its associated serious comorbidities. This meta-analysis aimed to investigate the relationship between psoriasis, dyslipidemia, and obesity. Two authors independently searched three databases (PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), The Cochrane Library, and Google Scholar).

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Obesity and type 2 diabetes mellitus (T2DM) are global health challenges. Bariatric surgery has emerged as a potential intervention for managing these conditions, but its efficacy and impact need comprehensive evaluation. This systematic review aimed to assess the impact of bariatric surgery on weight loss and glycemic control in patients with obesity and T2DM.

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Psoriasis is a systemic disease affecting various organs; however, it is usually thought of as a skin disease. A multidisciplinary approach is needed for better outcomes. The current meta-analysis assessed the association between diabetes mellitus, high blood pressure, and psoriasis.

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Article Synopsis
  • - The study evaluates the quality of life after two types of thyroidectomy: trans oral video-assisted thyroidectomy (TOVAT) and conventional transcervical thyroidectomy, finding that TOVAT patients have a better quality of life post-surgery.
  • - A comprehensive meta-analysis was conducted, filtering through 482 studies and ultimately reviewing six that met the criteria, revealing a significant advantage for TOVAT in patient outcomes at 4-6 weeks after surgery.
  • - Although TOVAT improved most quality of life aspects according to the SF-36 questionnaire, social and general health components were similar for both surgical methods, indicating the need for further research with larger sample sizes to better assess the results.
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Article Synopsis
  • Thyroid diseases are common but often go undiagnosed in Saudi Arabia due to a lack of symptoms and awareness among the population.
  • A survey conducted among 996 adults showed that while a significant portion knew about the thyroid gland and its functions, overall knowledge about hypothyroidism and hyperthyroidism was inadequate, particularly among certain demographics.
  • The study found that older women with higher education levels had the best understanding of thyroid disorders, highlighting the need for improved public health strategies to increase awareness in the broader population.
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Background: Periodontitis is the sixth most prevalent chronic disease. Literature suggests a relationship between diabetes and periodontitis and when coexist may aggravate each other deleterious consequences. Therefore, we aimed to assess the effects of periodontitis treatment on glycemic control.

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Background: Bariatric surgery is superior to usual care for diabetes remission. Previous meta-analyses were limited by pooling observational and randomized trials, using various definitions of diabetes remission, and not controlling for various diabetes medications. The current meta-analysis aimed to compare bariatric surgery and usual care regarding the same.

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Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most commonly used bariatric procedures. There is an increasing awareness about a comorbidity-based indication for bariatric surgery regardless of weight (metabolic surgery). The best operation to mitigate obesity-associated comorbidities is a matter of controversy.

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The pathogenesis of psoriasis involves the interaction of several environmental and genetic factors. Predicting the disease risk cannot depend on individual genetic alleles. Consequently, some studies have evaluated the use of genetic risk scores that combine several psoriasis susceptibility loci to increase the accuracy of predicting/diagnosing the disease.

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