Dual Mediating Effect of Electronic Device Utilization and Life Satisfaction on the Relationship between Instrumental Activities of Daily Living and Depression in Older Adults.

This study aimed to investigate the correlation between instrumental activities of daily living (IADL), depression, electronic device utilization (EDU) and life satisfaction in older adults and to evaluate the dual mediating effect of EDU and life satisfaction on the relationship between IADL and depression. A secondary data analysis of the 2020 Korean Elderly Survey was carried out with 9906 older adults. The dual mediating effect was analyzed using model 6 of PROCESS Macro for SPSS v.

Ethanol suppresses carbamylcholine-induced intracellular calcium oscillation in mouse pancreatic acinar cells.

Oscillation of intracellular calcium levels is closely linked to initiating secretion of digestive enzymes from pancreatic acinar cells. Excessive alcohol consumption is known to relate to a variety of disorders in the digestive system, including the exocrine pancreas. In this study, we have investigated the role and mechanism of ethanol on carbamylcholine (CCh)-induced intracellular calcium oscillation in murine pancreatic acinar cells.

Effect of burdock extracts upon inflammatory mediator production.

We investigated the burdock extract on the inhibitions of NO generation, COX-2 expression, and the generations of IL-6 and TNF-α , to find out its anti-inflammatory effect in this study. After the treatment of the burdock extract in the cells, we measured the amount of NO generated in the inflammatory cells developed by LPS and UVB, and confirmed the developments of inflammatory mediators by RT-PCR. Upon the results on the NO generation after the development of inflammation by LPS in Raw 264.