Publications by authors named "Hwa Hee Koh"
Several donor-specific factors influence the functional recovery and long-term outcomes of liver grafts. This study investigated the association between donor fasting glucose (DFG) and recipient outcomes after living donor liver transplantation (LDLT) in 950 cases at a single center. Patients were divided into two groups: low-DFG (< 85 mg/dL, n = 120) and control (≥ 85 mg/dL, n = 830).
View Article and Find Full Text PDFBackground: Living donor liver transplantation (LDLT) offers timely curative treatment for unresectable hepatocellular carcinoma (HCC). This study aims to validate and compare previous prediction models for HCC outcomes in 488 LDLT recipients.
Methods: For 488 patients who underwent LDLT for HCC, pretransplant imaging studies assessed by modified RECSIT criteria, tumor markers such as alpha feto-protein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA II), and explant pathology were recruited.
Article Synopsis
- * Patients with seizures have significantly lower five-year graft survival rates (50.6%) compared to those without (78.2%), and seizures increase the risk of graft loss by over double.
- * Key risk factors for post-liver transplant seizures include low body mass index, older donor age, use of renal replacement therapy during surgery, and elevated sodium levels, suggesting that managing these factors could prevent seizures and improve transplant outcomes.
Article Synopsis
- LDLT can provide better one-year survival rates for patients with high MELD scores compared to waiting for deceased-donor liver transplantation (DDLT) in regions with organ shortages.
- A study of 649 patients found that those who underwent LDLT had significantly lower mortality rates than those who were on the waitlist for DDLT.
- While LDLT has higher surgical complication rates, the outcomes for living donors were generally positive, with no reported fatalities and minimal severe complications.
Article Synopsis
- The study investigates the impact of albumin-bilirubin (ALBI) scores on the prognosis of colorectal cancer (CRC) patients after surgery.
- Researchers analyzed data from 723 surgical patients, comparing preoperative (ALBI-pre) and postoperative (ALBI-post) scores to determine their influence on overall survival (OS).
- The findings indicate that the combined ALBI-trend score (which considers changes from preoperative to postoperative scores) is a significant independent prognostic factor for OS, offering better predictive accuracy than ALBI-pre or ALBI-post scores alone.
Background: The albumin-bilirubin (ALBI) grade is a useful prognostic and predictive marker for patients with liver disease. Its clinical significance has been limited to patients with colorectal cancer (CRC). Furthermore, the association between the ALBI grade and skeletal muscle-related indices is unclear.
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