Racial Residential Segregation and Mental Health During Pregnancy.

Importance: Research suggests the social, physical, and socioeconomic contexts of residing in segregated neighborhoods may negatively affect mental health.

Objective: To assess the association between racial residential segregation and prenatal mental health among Asian, Black, Hispanic, and White individuals.

Design, Setting, And Participants: This population-based cross-sectional study was conducted in Kaiser Permanente Northern California (KPNC), an integrated health care delivery system.

Oral Antibiotic Use in Adulthood and Risk of Early-Onset Colorectal Cancer: A Case-Control Study.

Background And Aims: Prior antibiotic use may be a factor in the rising incidence of colorectal cancer seen in those under 50 years of age (early-onset colorectal cancer [EOCRC]); however, the few studies to examine this link have reported conflicting results. Therefore, we evaluated the association between oral antibiotic use in adulthood and EOCRC in a large integrated healthcare system in the United States.

Methods: A population-based nested case-control study was conducted among Kaiser Permanente Northern California patients 18-49 years of age diagnosed with EOCRC (adenocarcinoma of the colon or rectum) in 1998-2020 who had ≥2 years of continuous pharmacy benefit prior to diagnosis.

The automatic processing of social information in working memory.

Working memory has been considered an active buffer for processing perceptual representations in a progressive manner, integrating information involuntarily to form structured mental representations. The automatic integration of objects' physical features in working memory has been well documented, although its social aspect remains unknown. The current study examines whether working memory would automatically process social information, that is, extract social information from memory content to form a higher-level social representation.

The storage mechanism of dynamic relations in visual working memory.

The ability to briefly hold and manipulate object relations provides a foundation for interacting with our complex environment. Previous studies on working memory focused more on objects than their relations, which is disproportionate in the context of their theoretical importance. This study examined dynamic relations of objects to better understand the storage mechanism (capacity and representation) using a self-developed modified change detection paradigm, where an object moved dynamically, based on its relation to other objects.