Evaluation of a Novel Formaldehyde-Free Fixation Solution for the Fixation of Mouse Organs.

Objective: A new aldehyde-free fixative has been developed and its effect has been compared to traditional formaldehyde fixative in terms of the fixation effect and HE staining of the heart, liver, lung, and kidney. The air in the experimental area was examined to evaluate its impact on the environment and human health.

Methods: The organs from mice of groups 1-6 were taken respectively (thickness of liver and lung was 3 mm).