Publications by authors named "Huw Lewis Jones"
Background: The contemporary treatment of oropharyngeal squamous cell carcinoma (SCC) is an area of debate. We report outcomes of a minimally invasive approach involving transoral laser microsurgery (TLM).
Methods: A consecutive series of patients (n = 153) undergoing primary TLM for oropharyngeal SCC from 2006 to 2013 was studied.
We aim to compare radiological with histological tumour thickness (RTT with HTT) for oral squamous cell carcinoma (OSCC), and the ability of both to predict cervical metastasis. The MRI images and histopathology reports of 102 consecutive OSCC cases were compared and the relationship between RTT and HTT, calculated as a "shrinkage factor" by the gradient of the best fitting regression line. Most (69%) tumours appeared thicker on MRI than was revealed by histopathology.
View Article and Find Full Text PDFBackground: Extracapsular spread (ECS) in the cervical lymph nodes represents the most significant adverse prognostic indicator in oral squamous cell carcinoma (OSCC).
Methods: In a consecutive cohort of OSCC treated by primary surgery, ECS was seen in 25% (101) of 400 patients.
Results: ECS doubled the incidence of local recurrence and distant metastases, but tripled regional failure.
Article Synopsis
- Screening for pulmonary tumors in patients with squamous cell carcinoma of the head and neck (SCCHN) is crucial, as early detection can change treatment plans.
- A study of 1,882 patients showed a 4.3% rate of synchronous pulmonary tumors, highlighting different outcomes based on disease severity and tumor types.
- The research suggests using thoracic CT scans for all SCCHN patients to effectively identify any concurrent pulmonary issues, despite challenges in establishing specific screening guidelines for certain types of lung cancer.
Cerebral venous thrombosis is a relatively uncommon but serious neurological condition. It can have disastrous consequences if not diagnosed and treated promptly. It can be missed on initial presentation clinically as well as radiologically unless there is high level of suspicion.
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