Heart rate and heart rate variability changes in the intracarotid sodium amobarbital test.

Purpose: Changes in heart rate and heart rate variability have been found in prior studies performed during the intracarotid sodium amobarbital (ISA) test. However, these results are not entirely consistent with current models of differential cerebral involvement in the modulation of the heart. This study was designed to re-investigate this topic with a larger N than has heretofore been used.

Affective self-report during the intracarotid sodium amobarbital test: group differences.

Emotional reactions are sometimes observed during the intracarotid sodium amobarbital test. For instance, euphoric/indifference reactions can be seen during right hemisphere inactivation and catastrophic reactions may accompany left hemisphere inactivation. Less dramatic changes can also be detected in affective self-report during left and right hemisphere amobarbital tests, with more negative affect reported during left hemisphere inactivation and either neutral or mildly positive affective states reported during right hemisphere inactivation.

Response of human epileptic temporal lobe cortical blood flow to hyperventilation.

Bilateral long-term surface cortical cerebral blood flow (CBF) and electrocorticographic (ECoG) monitoring were performed in eight patients with complex partial seizures. In each patient, the epileptic temporal lobe was localized using ictal ECoG. Mean seizure interval (frequency-1) off anticonvulsant medication, a clinical measure of epileptogenicity, was 1.

Epileptic spasms in older children: persistence beyond infancy.

Although infantile spasms (IS) constitute a well-recognized epileptic syndrome, only recently did investigators propose that spasms be classified as a distinct seizure type, characterized by axial flexion/extension jerks in clusters. Five older children (aged 4.5-14.

Nursing implications of the intracarotid amobarbital procedure.

The intracarotid amobarbital procedure, by inactivation of each hemisphere, provides the opportunity to evaluate language and memory function of the individual considering epilepsy surgery. Careful explanation of this procedure, and its importance to the proposed surgery are vital to the patient's cooperation and performance during this examination. The neuroscience nurse has a significant role in the success of this procedure.

Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis.

Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital prior to surgery for intractable epilepsy. The electroencephalogram (EEG) of these patients was continuously monitored during these 74 procedures and was later subjected to quantitative analysis. Topographic mapping of these data suggested that the areas of inactivation were largely restricted to the anterior 2/3 of the hemisphere injected, corresponding to the vascular distributions of the anterior and middle cerebral arteries.

Immunodeficiency secondary to juvenile paracoccidioidomycosis: associated infections.

Four patients with acute paracoccidioidomycosis, hypoalbuminemia, ascites and associated infections are reported. They have been admitted to hospital 35 times, 4 of them due to active paracoccidioidomycosis, 14 to associated infections, 14 to ascites, edema and diarrhoea and 3 to herniorrhaphy. Two of them recovered after sepsis and central nervous system, muscular and subcutaneous cryptococcosis.

[Bone marrow involvement and eosinophilia in paracoccidioidomycosis].

The authors described three acute paracoccidioidomycosis patients with bone marrow involvement. P. brasiliensis yeast forms were observed in bone marrow smears of all them, and in one case, culture also revealed fungus growth.

Mathematical model of Klebsiella pneumoniae resistance to amikacin and gentamicin.

1. The resistance of Klebsiella pneumoniae to amikacin and gentamicin was studied by a mathematical model to predict the rate of sensitivity decrease. The results accurately matched experimental data, showing that the model is a reliable predicting tool.

Activity of fosfomycin in the treatment of bacterial infections.

30 patients with different infections were treated with fosfomycin: 13 had urinary infections, 14 had pneumonial infections, 2 had staphylococcus osteomyelitis and 1 had staphylococcus septicemia. The antibiotic was administered in doses ranging from 100 to 230 mg/kg/day, with periods of treatment that lasted from 5 to 58 days. The doses were administered every 6 h by the oral or intramuscular route.