Publications by authors named "Hussein Mackie"

Article Synopsis
  • This study aimed to evaluate the accuracy of Beta-2 transferrin (B2Tf) gel electrophoresis in diagnosing cerebrospinal fluid (CSF) rhinorrhea among patients with unilateral thin clear rhinorrhea (UTCR), a condition that can indicate various medical issues. !* -
  • Conducted from 2016 to 2024, the study involved 105 patients and showed B2Tf GE had a sensitivity of 89.5% and specificity of 78.3%, with certain causes for false results identified, such as sinusitis and contamination during sample collection. !* -
  • While the findings align with previous literature on test accuracy, the study highlights the need for further research
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Objective: Topical nasal decongestants (TNDs) are used to reduce nasal soft tissue edema and obstruction. However, after frequent TND use, patients can develop rhinitis medicamentosa (RM) with rebound nasal edema and obstruction. Management of RM has centered largely on TND cessation ± intranasal corticosteroids.

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Objectives: Unilateral clear thin rhinorrhea (UCTR) can be concerning for a nasal cerebrospinal fluid (CSF) leak. Beta-2 transferrin electrophoresis has been the gold standard for initial non-invasive confirmatory testing for CSF rhinorrhea, but there can be issues with fluid collection and testing errors. Ipratropium bromide nasal spray (IBNS) is highly effective at reducing rhinitis-related rhinorrhea, and should presumably not resolve CSF rhinorrhea.

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