Exacerbation of Fragile X-associated Tremor/Ataxia Syndrome in the Context of COVID-19 Infection: A Case Report.

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting premutation carriers of the FMR1 gene. This case report presents a 65-year-old male who was diagnosed with FXTAS after presenting with an acute exacerbation of neurological symptoms in the setting of a COVID-19 infection. The case highlights the potential for viral infections to trigger the worsening of FXTAS symptoms and emphasizes the importance of comprehensive evaluation in such scenarios.

Frailty Does Not Impact Caregiver Burden in Patients with Cirrhosis.

Background: Frailty is common and is associated with increased mortality, lower quality of life, and higher readmission rates in cirrhotic patients. Not only are these outcomes important, but further understanding the impact of frailty on a caregiver's life is crucial to better comprehend caregiver burden in cirrhotic patients and develop strategies to improve care for patients and their caregivers.

Methods: A single-center, prospective study was conducted of cirrhotic patients and their caregivers between 4/1/2019 and 11/1/2019.