Phytochemical composition and antidiabetic, anti-obesity, antioxidant, and cytotoxic activities of Carthamus tinctorius seed oil.

Carthamus tinctorius L. (Safflower) is widely used in traditional Japanese, Korean, Chinese, Arabian, and Persian herbal medicine to treat metabolic diseases. This study aimed to characterize C.

Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing BiO, PbO, or BiO/PbO Nanoparticles.

Background: Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life.

Objective: This study aimed to prepare flexible silicone-based matrices containing BiO, PbO, or BiO/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.

Material And Methods: In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles.

Successful management of a multi-species outbreak of carbapenem-resistant organisms in Fiji: a prospective genomics-enhanced investigation and response.

Background: Fiji is a Pacific Island nation grappling with the increasing threat of antimicrobial resistance (AMR). While genomic technologies are increasingly utilised to understand the emergence and spread of AMR globally, its application to inform outbreak responses in low- and middle-income settings has not been reported.

Methods: Through an established capacity building program, suspected carbapenem-resistant organisms (CRO) identified at Colonial War Memorial Hospital in Fiji (Jan 2022-Oct 2023) underwent whole genome sequencing and analysis.

Ambiance as a Key for a Better Birth Experience.

This research provides insights into childbirth as a sensitive experience, from the perspective of its user, "woman in labour," as well as from the perspective of the event itself, "the childbirth," and the birth space, with its spatial and ambiantal configurations. By adopting an in-situ approach, we conducted a spatial and ambiantal characterization of two childbirth different contexts; Tunis and Grenoble. Along this work, we used various methods such as ethnographic observation and semistructured interviews with mothers and midwives, when following visits to the birth spaces in Grenoble.

Quantitative Determination of Salivary Cariogenic Bacteria in Patients With Fixed Orthodontic Appliances.

Background And Objectives: Fixed orthodontic treatment can alter the oral environment, potentially increasing cariogenic bacteria levels. This study aimed to utilize real-time polymerase chain reaction (qPCR) to quantify salivary levels of cariogenic bacteria in patients undergoing orthodontic treatment with fixed appliances.

Methods: This case-control study was conducted in Erbil, Iraq, from April 2024 to August 2024.

Electronic Coupling in Triferrocenylpnictogens.

From a fundamental perspective, studies of novel mixed-valent complexes containing ferrocenyl units are motivated by the prospect of improving and extending electron transfer models and theories. Here, the series of triferrocenylpnictogens FcE was extended to the heavier analogues (E = As, Sb, and Bi), and the influence of the bridging atom was investigated with FcP as a reference. Electrochemical studies elucidate the effect of electrostatic contribution on the large redox splitting (Δ ) exhibited by the compounds and solvent stabilization in the case of FcAs.

Insights into free radicals scavenging, α-Amylase inhibition, cytotoxic and antifibrotic activities unveiled by Peganum harmala extracts.

Background: Peganum harmala L. is used in traditional medicine to treat several health ailments. Hence, the present work aimed to investigate the DPPH free radical scavenging, α-amylase, cytotoxic, and antifibrotic effects of the hydrophilic extract and fixed oil obtained from P.

Bladder cancer with bone marrow metastases and thrombotic microangiopathy: a case report.

Bladder cancer is one of the most common cancers of the urinary tract and the 10th most common cancer worldwide according to the World Health Organization (WHO), with a higher incidence in men than in women. Bladder cancer rarely presents with a clinical picture of bone marrow infiltration which may result in thrombotic microangiopathy (TMA). TMA is a syndrome triggered by a wide variety of conditions, some of which are associated with cancer.

Prevalence of burnout and associated factors among midwives, 2023: institution-based cross-sectional study.

Background: One of the main characteristics of the mental health condition known as burnout syndrome is an overwhelming feeling of physical and emotional tiredness, particularly with regard to one's work. Midwives are the group most prone to burnout because they work in emergency situations to save two lives at a time, share the stress of laboring women, and put in extra hours without enough payment. Besides this, there is little information on burnout among Ethiopian midwives.

Folic acid-modified nanocrystalline cellulose for enhanced delivery and anti-cancer effects of crocin.

Crocin is a carotenoid compound in saffron with anti-cancer properties. However, its therapeutic application is limited by its low absorption, bioavailability, and stability, which can be overcome through nanocarrier delivery systems. This study used surface-modified Nano-crystalline cellulose (NCC) to deliver crocin to cancer cells.

Biological, phytochemical and molecular docking characteristics of Laurus nobilis L. fresh leaves essential oil from Palestine.

Background: The historical use of Laurus nobilis L., the plant is native to the Mediterranean region and has been cultivated for its aromatic leaves, which are used as a flavoring agent in cooking and for their potential therapeutic properties.

Methods: The purpose of the current investigation was to characterize the essential oil composition of the fresh L.

Addressing Kidney Transplant Shortage: The Potential of Kidney Paired Exchanges in Jordan.

Jordan performed the Middle East's first living-donor kidney transplant in 1972. In 1977, the country became one of the first Arab countries to regulate organ donation and transplantation. Despite these early advances in living donor transplantation, Jordan's organ donation after brain death program remains inactive, making it challenging to meet organ demand and placing many patients on long transplant waiting lists.

Pharmacy Students' Perception of the Content and Delivery of Drug Information Training: A Mixed-Methods Study.

Objective: To explore the pharmacy students' perception of the content and pedagogical strategies used for the delivery of drug information (DI) training.

Methods: An explanatory sequential mixed-methods study was conducted among BSc Pharmacy and PharmD students at the College of Pharmacy, Qatar University. The first phase consisted of a quantitative cross-sectional survey using a 34-item pretested questionnaire.

Total phenolic contents, cytotoxic, free radicals, porcine pancreatic α-amylase, and lipase suppressant activities of plant from Palestine.

Artemisia dracunculus: L. () is a popular vegetable and spice cultivated across many Middle Eastern countries. The herb's aqueous extract has significant folkloric medicinal importance for treating various disorders.

Maternal delay for institutional delivery and associated factors among postnatal mothers at Southeastern Ethiopia: a cross sectional study.

Background: Maternal delay in timely seeking health care, inadequate health care and the inability to access health facilities are the main causes of maternal mortality in low and middle income countries. The three-delay approach was used to pinpoint responsible factors for maternal death. There was little data on the delay in decision making to seek institutional delivery service in the study area.

Secondary amenorrhea as the first presentation of Krukenberg tumor arising from the gastroesophageal junction in a 34-year-old woman: A case report.

Introduction: Krukenberg tumors account for 9 % of metastatic ovarian tumors, they usually originate from the stomach and colon and are microscopically characterized by the presence of mucus-filled signet-ring cells. Krukenberg tumor originating from the gastroesophageal junction is extremely rare, which limits establishing proper diagnosis and management.

Presentation Of Case: A 34-year-old women presented with a complaint of amenorrhea, ultrasonography showed bilateral ovarian masses, pathological studies revealed Krukenberg tumor, immunohistochemistry of the tumor was positive for (CK1, and CK20).

Clinical Evaluation of Single Versus Repeated Micro-Osteoperforations During Orthodontic Canine Retraction: A Randomized Clinical Trial.

Introduction: In the majority of orthodontic premolar extraction cases, the canine retraction phase is the most laborious procedure. This randomized clinical trial aimed to assess the effect of single versus repeated micro-osteoperforations (MOPs) during orthodontic canine retraction.

Methods: In this split-mouth study, two equal groups of 18 patients who required maxillary first premolar extractions and fixed orthodontic therapy were randomly assigned (n=9).

Plasma cell leukemia in a 34-year-old male: rare scenario case report.

Introduction: Plasma cell leukaemia is an uncommon plasma cell dyscrasia with a very poor prognosis. It is more common among males and usually presents between 55 and 65 years of age.

Case Presentation: A 34-year-old male presented to Al-Assad hospital with unremitting back pain.

An ethno-botanical study of medicinal plants used for the management of respiratory tract disorders in northern parts of Palestine.

Background: The medicinal application of natural plant remedies is well established. These medicinal plants are still in use within the Palestinian community to treat several illnesses. This research is intended to study the use of natural plants to treat different types of respiratory tract disorders.

Evaluating Sustainable Development Pathways for Protein- and Peptide-Based Bioadsorbents for Phosphorus Recovery from Wastewater.

Recovering phosphate (P) from point sources such as wastewater effluent is a priority in order to alleviate the impacts of eutrophication and implement a circular economy for an increasingly limited resource. Bioadsorbents featuring P-binding proteins and peptides offer exquisite P specificity and sensitivity for achieving ultralow P concentrations, i.e.

Ex vivo treatment with poly (I:C) alleviates the exhausted phenotype of tumor-infiltrating TCD8 cells of gastric cancer patients.

Gastric cancer is associated with the phenotypic and functional exhaustion of TCD8 cells. On the other hand, Toll-like receptor (TLR) agonists are known to reinforce immune responses when used as adjuvants in cancer immunotherapies. Since the compromised signaling of pro-inflammatory pathways is usually associated with T cell exhaustion, the aim of the present study was to evaluate the impact of polyinosinic-polycytidylic acid (poly (I:C))-mediated TLR3 activation in restoring the normal phenotype and function of tumor-infiltrating TCD8 cells.

Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways.

Alzheimer's disease (AD) is a devastating illness with limited therapeutic interventions. The aim of this study is to investigate the pathophysiological mechanisms underlying AD and explore the potential neuroprotective effects of cocoa, either alone or in combination with other nutraceuticals, in an animal model of aluminum-induced AD. Rats were divided into nine groups: control, aluminum chloride (AlCl) alone, AlCl with cocoa alone, AlCl with vinpocetine (VIN), AlCl with epigallocatechin-3-gallate (EGCG), AlCl with coenzyme Q10 (CoQ10), AlCl with wheatgrass (WG), AlCl with vitamin (Vit) B complex, and AlCl with a combination of Vit C, Vit E, and selenium (Se).

Treatment effects of Herbst appliance in skeletal Class II cases during pre-pubertal and post-pubertal periods: a cone-beam computed tomographic study.

In the present study, Thirty-six Class patients II (A condition in which the upper jaw is larger than the lower jaw) were randomly selected and assigned to one of two groups based on their maturation stage: the pre-pubertal group (18 patients, mean age 9.15 ± 1.5 years) and post-pubertal group (18 patients, mean age 16.

A Rare Manifestation of Unknown Hyperparathyroidism as a Perforated Peptic Ulcer.

Hypercalcemia is a common electrolyte abnormality with different causes. Hypercalcemia is most often associated with malignancy and primary hyperparathyroidism and malignancy together account for most cases. Primary hyperparathyroidism manifests as hypercalcemia owing to the overproduction of parathyroid hormone.