Serum uric acid: an independent risk factor for cardiovascular disease in Pakistani Punjabi patients.

Background: It is well-known that serum uric acid (SUA) can increase the risk of hypertension, diabetes, obesity and dyslipidemia. However, its independent association with the risk of cardiovascular diseases (CVD) is controversial particularly in different populations. Hence, this study was aimed to assess an independent association of SUA with CVD risk in a Punjabi Pakistani cohort.

Exploring topological indices and entropy measure via rational curve fitting models for calcium hydroxide network.

This work uses rational curve fitting models to investigate the complex link between topological indices and entropy metrics in calcium hydroxide networks. Entropy measurements shed light on the complexity and disorder of these networks, whereas topological indices are essential instruments for comprehending the structural characteristics of chemical substances. Our goal is to find new patterns and connections by merging these two fields, improving materials science's prediction capacity.

Molecular detection and phylogenetic analysis of ovine herpesvirus-2 in subclinical infections of cattle and sheep.

Ovine herpesvirus-2 (OvHV-2) is the causative agent of malignant catarrhal fever (MCF), a serious and often fatal disease that affects cattle and other ruminants. This study aimed to investigate the molecular epidemiology and genetic diversity of OvHV-2 strains circulating in sheep and cattle populations in the Jammu and Kashmir region of India. Screening of 150 sheep and 57 cattle blood samples revealed the presence of the OvHV-2 polymerase (pol) gene in 8.

Synthesis and optimization of molecular weight of chitosan and carboxymethyl cellulose based polyurethanes.

For the first time in this research, using a mixture design approach, polyurethanes (PUs) based on chitosan (CSN) and carboxymethyl cellulose (CMC) were synthesized to develop a high molecular weight polymer. In the synthesis process, a reaction between isophorone diisocyanate (IPDI) and hydroxyl-terminated polybutadiene was carried out to synthesize a prepolymer containing free NCO groups at the corners. This prepolymer was further reacted with changing moles ratio of CSN and CMC following the principles of statistical mixture design.

Understanding disparities in cardiovascular death rates among older adults with sick sinus syndrome in the US.

Background: Sick sinus syndrome (SSS) increases with age, and approximately one in 600 patients above 65 develop this condition. In this study, the authors assessed trends in mortality related to SSS among older adults ≥65 years of age in the United States from 1999 to 2019.

Methods: Trends in cardiovascular mortality related to SSS were identified by analyzing the data from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database, where cardiovascular deaths were listed as the underlying cause of death and SSS was listed as the contributing cause of death between 1999 and 2019.

Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents.

Drug-eluting stents are commonly utilized for the treatment of coronary artery disease, where they maintain vessel patency and prevent restenosis. However, problems with prolonged vascular healing, late thrombosis, and neoatherosclerosis persist; these could potentially be addressed via the local generation of nitric oxide (NO) from endogenous substrates. Herein, we develop amine-functionalized graphene as a NO-generating coating on polylactic acid (PLA)-based bioresorbable stent materials.

An Alternative Diagnostic Test rather than 24 hours Urinary Protein to Detect Massive Proteinuria in Nephrotic Syndrome in Mymensingh Medical College Hospital, Bangladesh.

This cross-sectional study was conducted in Department of Paediatrics, Mymensingh Medical College Hospital (MMCH), Bangladesh from February 2016 to December 2016 to detect massive proteinuria by spot urinary protein creatinine ratio as an alternative diagnostic test to 24 hrs urinary total protein in nephrotic syndrome. Fifty one (51) children aged 2 to 12 years admitted with 1st episode of nephrotic syndrome in the pediatric department of MMCH were included in this by purposive sampling technique. All the patients were asked to give a 24 hours urine sample.

Facile Biogenic synthesis of Europium doped lanthanum silicate nanoparticles as novel supercapacitor electrodes for efficient energy storage applications.

In this work, we demonstrated for the first time, use of Europium doped lanthanum silicate nanoparticles (LS NPs) as electrodes for supercapacitor applications. Europium (Eu) doped (5 mol%) LS NPs were synthesized by green solution combustion method using Mexican mint leaf extracts. Various analytical techniques such as High-Resolution Transmission Electron Microscopy (HRTEM), Selected Area Diffraction (SAED), Powder X-ray Diffraction (PXRD), Fourier Transform Infra-Red Spectroscopy (FTIR) and Diffuse Reflectance Spectroscopy (DRS) techniques were used to confirm the morphological and structural characteristics of the synthesized nanoparticles.

The mutant STAY-GREEN () in cucumber interacts with the CSEP30 protein to elicit a defense response against .

Unlabelled: Disease-resistant plants activate immune responses by specifically recognition Candidate Secreted Effector Proteins (CSEPs) through resistance (R) proteins. In research on cucumber powdery mildew resistance breeding, several R genes and CSEPs have been identified; however, the specific interactions between R proteins and CSEPs are still largely unexplored. In this study, we used a luciferase reporter assay to identify six CSEPs from that potentially induce cell death in cucumber.

Rapid fabrication of polyoxometalate-enhanced photo responsive films from ethyl cellulose (EC) and polyvinylpyrrolidone (PVP).

Ethyl cellulose (EC), polyvinylpyrrolidone (PVP), and phosphomolybdic acid (PMoA) were the components of a new photochromic hybrid film composed of heteropoly acids (abbreviated EC-PVP/PMoA), created by solvent evaporation. The EC-PVP/PMoA mechanism, visible light photochromic behaviors, and microstructure were closely studied by transmission electron microscopy (TEM), atomic force microscopy (AFM), ultraviolet-visible (UV-visible) spectroscopy, X-ray photo electronics (XPS), and Fourier transmission infrared spectroscopy (FTIR). FTIR spectra show that neither the core structures of EC, PVP, nor the Keggin structure of PMoA in the EC-PVP/PMoA composite hybrid film were damaged during fabrication.

Treatment Outcomes and Definition Inconsistencies in High-Risk Unilateral Retinoblastoma.

Purpose: To compare the clinical outcomes of children with unilateral retinoblastoma (Rb) and high-risk histopathology features (HRHF) following upfront enucleation with/without adjuvant chemotherapy, and investigate cases locally considered non-HRHF but converted to a standardized HRHF definition.

Design: Retrospective multinational clinical cohort study.

Methods: Children with Rb who presented to 21 centers from 12 countries between 2011-2020, and underwent primary enucleation were recruited.

Beyond the Genome: Deciphering the Role of MALAT1 in Breast Cancer Progression.

The MALAT1, a huge non-coding RNA, recently came to light as a multifaceted regulator in the intricate landscape of breast cancer (BC) progression. This review explores the multifaceted functions and molecular interactions of MALAT1, shedding light on its profound implications for understanding BC pathogenesis and advancing therapeutic strategies. The article commences by acknowledging the global impact of BC and the pressing need for insights into its molecular underpinnings.

Recurrent stroke admissions with without COVID-19 and associated in-hospital mortality: A United States nationwide analysis, 2020.

Background: Coronavirus disease 2019 (COVID-19) has been shown to increase the risk of stroke. However, the prevalence and risk of recurrent stroke in COVID-19 patients with prior stroke/transient ischemic attack (TIA), as well as its impact on mortality, are not established.

Aim: To evaluate the impact of COVID-19 on in-hospital mortality, length of stay, and healthcare costs in patients with recurrent strokes.

Outdoor thermal sensation scale through biometeorological assessment for semi-arid climate.

Extreme temperatures in urban areas cause discomfort leading to a rise in health risks, like heat-related mortality (hyperthermia). It is, hence, important to have a comfortable thermal environment. Assessing outdoor thermal comfort is challenging and complicated due to its dependencies on biometeorological and psychological factors.

Positive Autism Screening Rates in Toddlers Born During the COVID-19 Pandemic.

Importance: Stress and viral illness during pregnancy are associated with neurodevelopmental conditions in offspring. Autism screening positivity for children born during the pandemic remains unknown.

Objective: To examine associations between prenatal exposure to the pandemic milieu and maternal SARS-CoV-2 infection with rates of positive Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R) screenings.

Exploring the experiences of people with obesity and post-bariatric surgery patients after three months using the mindful eating reflective practice: An interpretative phenomenological analysis.

Experiential dimensions of Mindful Eating Practices are scarce in the literature. Aim: The study focuses on thirteen individuals with clinical obesity and nine post-bariatric surgery patients who engaged in MERP over three months. The present research utilized Interpretative Phenomenological Analysis (IPA) as the analytical framework of interviews.

Effect of stroke etiology on treatment-related outcomes in young adults with large vessel occlusion: Results from a retrospective cohort study.

Introduction: Large vessel occlusion-acute ischemic stroke (LVO-AIS) is infrequent in young adults and exhibits distinct stroke mechanisms compared to older adults. This study sought to evaluate the impact of varying stroke etiologies on treatment-related outcomes in young adults with LVO-AIS, an aspect that remains unclear.

Methods: This retrospective cohort study included patients aged 18-50 presenting with AIS from January 2017 to December 2021 within our multi-center stroke network.

Pesticides under the category of persistent organic pollutants and emerging contaminants in surface sediments of an Arctic Fjord and nearby lakes.

This study focuses on the distribution of some selected organochlorine pesticides and emerging contaminants within the surface sediments of an Arctic fjord, Kongsfjorden and nearby lakes. Organochlorine pesticides (OCPs) such as dicloran, p,p'-DDT, p,p'-DDE, p,p'-DDD were studied along with five emerging contaminants namely diuron, chlorpyrifos, dicofol, pendimethalin and bifenthrin. The highest values of OCPs recorded among the fjord and lake environments during the time of study was 0.