Publications by authors named "Husniye Hande Aydin"
Article Synopsis
- A novel formulation of tedizolid phosphate (TZP) nanoparticle-loaded buccal films was developed to treat buccal wounds infected with Staphylococcus aureus.
- The optimal nanoparticle (NP) formulation was characterized and incorporated into mucoadhesive buccal films, demonstrating effective antibacterial properties in both in vitro and in vivo studies.
- The study found that the TZP-NP-loaded films significantly reduced bacterial counts and effectively inhibited S. aureus growth in wound samples, indicating their potential for long-lasting antibacterial treatment of buccal wounds.
Inflammatory diseases including rheumatoid arthritis are major health problems. Although different techniques and drugs are clinically available for the diagnosis and therapy of the disease, novel approaches regarding radiolabeled drug delivery systems are researched. Hence, in the present study, it was aimed to design, prepare, and characterize Tc-radiolabeled and tofacitinib citrate-encapsulated microsphere loaded poloxamer in situ gel formulations for the intra-articular treatment.
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